Results 21 to 30 of about 22,504 (208)

Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design

open access: yesMolecules, 2022
Mirtazapine is a tetracyclic anti-depressant with poor water solubility. The aim of this study was to improve the dissolution rate of mirtazapine by delivering the drug as a liquisolid compact.
Faiza Naureen   +12 more
doaj   +1 more source

Cost-effectiveness analysis of pharmaceutical treatment options in the first-line management of major depressive disorder in Belgium [PDF]

open access: yes, 2014
The objective of this study was to assess the cost effectiveness of commonly used antidepressants as first-line treatment of major depressive disorder (MDD) in Belgium.
Annemans, Lieven   +5 more
core   +2 more sources

Late-life depression : issues for the general practitioner [PDF]

open access: yes, 2018
Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints ...
Declercq, Tom   +4 more
core   +1 more source

Antidepressants in Alzheimer’s Disease: A Focus on the Role of Mirtazapine

open access: yesPharmaceuticals, 2021
Mirtazapine belongs to the category of antidepressants clinically used mainly in major depressive disorder but also used in obsessive-compulsive disorders, generalized anxiety, and sleep disturbances.
Ana Salomé Correia, Nuno Vale
doaj   +1 more source

A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators [PDF]

open access: yes, 2017
INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option.
Borenstein M   +8 more
core   +2 more sources

The still under-investigated role of cognitive deficits in PML diagnosis [PDF]

open access: yes, 2017
Background: Despite cognitive deficits frequently represent the first clinical manifestations of Progressive Multifocal Leukoencephalopathy (PML) in Natalizumab-treated MS patients, the importance of cognitive deficits in PML diagnosis is still under ...
Amato, Maria Pia   +49 more
core   +2 more sources

A double blind, fixed blood-level study comparing mirtazapine with imipramine in depressed in-patients [PDF]

open access: yes, 1996
Antidepressant effects of mirtazapine and imipramine were compared in a randomized, double blind, fixed blood-level study with in-patients in a single centre.
Broek, W.W. (Walter) van den   +6 more
core   +1 more source

Context-dependent effects of a single administration of mirtazapine on the expression of methamphetamine-induced conditioned place preference

open access: yesFrontiers in Behavioral Neuroscience, 2012
Re-exposure to cues repeatedly associated with methamphetamine (Meth) can trigger Meth-seeking and relapse in the abstinent abuser. Weakening the conditioned Meth-associated memory during cue re-exposure may provide a means for relapse-reduction ...
Robin eVoigt, T. Celeste eNapier
doaj   +1 more source

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

open access: yesClinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond   +2 more
wiley   +1 more source

Strategic use of new generation antidepressants for depression: SUN(^_^)D study protocol [PDF]

open access: yes, 2011
Background After more than half a century of modern psychopharmacology, with billions of dollars spent on antidepressants annually world-wide, we lack good evidence to guide our everyday decisions in conducting antidepressant treatment of patients with ...
Toshi A Furukawa   +7 more
core   +1 more source

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