Results 101 to 110 of about 75,905 (309)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The effect of miniscalpel acupuncture and splint treatment for joint deformity of hand osteoarthritis: a case report

open access: yesIntegrative Medicine Research, 2019
We are reporting the combined therapeutic effect of miniscalpel acupuncture and splint therapy on osteoarthritis of the hand accompanying severe joint deformity.
Kyongha Cho   +2 more
doaj   +1 more source

Comparative Response of Two Hydrilla Strains to Fluridone [PDF]

open access: yes, 2005
Experiments were conducted in a controlled-environmental growth chamber to evaluate the response of two strains of the invasive submersed plant Hydrilla verticillata (L.f.) Royle to fluridone (1-methyl-3-phenyl-5-[3-trifluoromethyl)phenyl]- 4(1H ...
Getsinger, K. D.   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Licorice ethanol extract improves symptoms of polycytic ovary syndrome in Letrozole-induced female rats

open access: yesIntegrative Medicine Research, 2018
Background: Licorice (Glycyrrhizae radix et rhizome, GRR) has long been used as an ingredient in Korean traditional medicinal herbal formulas for various metabolic and reproductive diseases. Polycystic ovary syndrome (PCOS) is a common endocrine disorder
Hyun Yang   +3 more
doaj   +1 more source

Organic beef and sheep production (OF0147) [PDF]

open access: yes, 2001
This is the final report from Defra project OF0147 To study the potential of organic farming in the hills and uplands, a comparison of organic and conventional production systems at similar stocking rates was made at ADAS Redesdale.
Keatinge, Ray
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The Baptist Church in Warren: Rehabilitation and Preservation Report [PDF]

open access: yes, 2013
The Baptist Church in Warren is located in the Warren Waterfront Historic National Register District. Warren also has a Voluntary Historic District. Both the National Register Nomination and the Voluntary Historic District have regulations which pertain ...
Bambara, Lauren   +4 more
core   +1 more source

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