Results 131 to 140 of about 70,792 (264)

Do preclinical seizure models predict success or failure in anti‐seizure drug development? A retrospective analysis of 89 compounds with divergent clinical outcomes for epilepsy

Epilepsia, EarlyView.
Abstract Anti‐seizure medication (ASM) discovery remains a major challenge despite over 30 commercially available options. One persistent obstacle for any promising candidate compound to successfully move from preclinical study to clinical approval has been the ambiguity in preclinical model selection.
Wolfgang Löscher, Melissa Barker‐Haliski   +1 more
wiley   +1 more source

Evaluating the impact of an AI‐powered chatbot on epilepsy education and stigma reduction: A pre‐post intervention study using EpiloBot

Epilepsia Open, EarlyView.
Abstract Objective Effective epilepsy management requires accurate epilepsy knowledge, active patient engagement, and stigma reduction to improve health outcomes. Educational interventions have been shown to enhance patients' quality of life (QOL) and knowledge. This study evaluated the effectiveness of EpiloBot, an artificial intelligence (AI)‐powered
Izumi Kuramochi, Ryoya Oba, Naoki Nozawa, Tomoki Ishihara, Koko Oga, Takayuki Iwayama, Takafumi Shiganami, Sayaka Kobayashi, Hironori Kuga, Haruo Yoshimasu, Keiichi Watanuki   +10 more
wiley   +1 more source

Knowledge of Antibiotic Resistance Among Dental Students at Teerthanker Mahaveer University: A Cross-Sectional Study. [PDF]

Cureus
Pertin N, Jain A, Tangade P, Singh V.
europepmc   +1 more source

Natural language processing‐based emotion and usage analysis of an AI‐powered chatbot for epilepsy support

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki, Ryoya Oba, Naoki Nozawa, Tomoki Ishihara, Koko Oga, Takayuki Iwayama, Takafumi Shiganami, Sayaka Kobayashi, Hironori Kuga, Haruo Yoshimasu, Izumi Kuramochi   +10 more
wiley   +1 more source

Public knowledge, beliefs and behaviours related to antimicrobial resistance and antibiotics: a systematic review of studies in high-income countries. [PDF]

JAC Antimicrob Resist
Shields C, Epton T, Berry E, Sahm LJ, Fleming A, Lambrou I, Feeney R, Sahar NU, Dobbs M, Kandulu CC, Melia E, Shorter GW.   +11 more
europepmc   +1 more source

Prepare, don't scare: Rethinking cognitive readiness before epilepsy surgery

Epilepsia Open, EarlyView.
Abstract Epilepsy surgery is an effective but underutilized treatment for drug‐resistant epilepsy, and concerns about postsurgical cognitive change are a prominent barrier. Refinements in surgical technique can reduce cognitive impact, but cognitive change cannot always be avoided, and approaches carrying lower cognitive risk are often less effective ...
Kayela Arrotta, Sofia Lesica, Hien Luu, Sallie Baxendale   +3 more
wiley   +1 more source

Closing Treatment Gaps for Polyendocrine Metabolic Ovarian Syndrome in India. [PDF]

J Med Internet Res
Thampi B.
europepmc   +1 more source

Clinical efficacy and cost‐effectiveness of epilepsy surgery in low‐ and middle‐income countries: A systematic review and meta‐analysis

Epilepsia Open, EarlyView.
Abstract Objective To synthesize evidence on clinical outcomes, direct surgical costs, and cost‐effectiveness of resective epilepsy surgery for drug‐resistant epilepsy in low‐ and middle‐income countries (LMICs). Methods MEDLINE, PubMed, Scopus, and the Cochrane Library were searched through May 17, 2026.
Muhamad Thohar Arifin, Firman Pribadi, Nurettin Öner   +2 more
wiley   +1 more source

A scoping review of pre-exposure prophylaxis awareness, acceptability, uptake, adherence, and HIV-related risk behaviors among university students in South Africa. [PDF]

Front Public Health
Serebane MJ, Ramavhoya TI, Mutshatshi TE, Mokhwelepa LW.   +3 more
europepmc   +1 more source

Next‐Generation Seismic Performance Assessment Through Multi‐Component Ground Motion Compatible Intensifying Artificial Acceleration

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Despite the crucial need for fully quantitative risk assessment of large‐scale structures, their performance is typically assessed through deterministic or semi‐quantitative approaches. The main preventing factor is the computational burden of probabilistic seismic analyses.
M. Amin Hariri‐Ardebili, Giacomo Sevieri, Carlo Resta, Golsa Mahdavi, Anna De Falco, Siamak Sattar, Sissy Nikolaou   +6 more
wiley   +1 more source