Results 191 to 200 of about 32,684 (231)

Pervasive mislocalization of pathogenic coding variants underlying human disorders

Cell
Widespread sequencing has yielded thousands of missense variants predicted or confirmed as disease causing. This creates a new bottleneck: determining the functional impact of each variant-typically a painstaking, customized process undertaken one or a ...
Jessica Lacoste, Marzieh Haghighi, Chloe Reno   +2 more
exaly   +2 more sources

Controlling CENPA mislocalization [PDF]

Nature Reviews Molecular Cell Biology, 2014
exaly   +2 more sources

Mislocalization in Plasmon-Enhanced Single-Molecule Fluorescence Microscopy as a Dynamical Young’s Interferometer

ACS Photonics, 2018
Harrison J Goldwyn, Kevin C Smith, Jacob A Busche   +2 more
exaly   +2 more sources

Dodging mitochondrial mislocalization

Nature Reviews Molecular Cell Biology
exaly   +3 more sources

Mislocalization of diplopic images

Journal of the Optical Society of America A, 1988
When observers dichoptically view bar stimuli at disparities beyond the fusion limit, the bars are perceived as being closer together than they really are. When 6.0-cycle/deg vertical derivative-of-Gaussian bars are adjusted into apparent alignment with binocularly presented spots, the mislocalization of each bar's half-image is typically 2-5 arcmin ...
D, Rose, R, Blake
openaire   +2 more sources

Motion mislocation

Optical Society of America Annual Meeting, 1991
Pairs of dots in apparent motion are strikingly mislocalized in the direction of the motion. If two pairs of dots in horizontal apparent motion, moving in opposite directions are positioned one over the other (forming a tall rectangle), they do not appear vertically aligned.
Leslie Welch, Donald I. A. MacLeod
openaire   +1 more source

Perisaccadic mislocalization in dyslexia

Neuropsychologia, 2009
Evidence from experiments designed to elicit the phenomenon of perisaccadic mislocalization of briefly presented probe stimuli suggests that mechanisms implicated in the planning of a saccade are also implicated in the means by which spatial constancy is maintained across saccades. We postulated that impairments of visual attention observed in dyslexic
Elizabeth, Liddle, Yu Ju, Chou, Stephen, Jackson   +2 more
openaire   +2 more sources

Objective Measurement of Tactile Mislocalization

IEEE Transactions on Biomedical Engineering, 2005
Stimulating the skin with intensities close to the sensory threshold causes erroneous localization of the site of stimulation. Previous studies using manual methods for applying faint tactile stimuli have shown that localization errors obey a somatotopic principle in which tactile stimuli are preferentially mislocalized to sites adjacent to the ...
Braun, Heinrich Christoph, LADDA J, BURKHARDT M, WIECH K, PREISSL H, ROBERTS L.   +5 more
openaire   +3 more sources

Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress

Nature Neuroscience
Aging is one of the most prominent risk factors for neurodegeneration, yet the molecular mechanisms underlying the deterioration of old neurons are mostly unknown.
Kevin Rhine, Rachel Li, Hema M. Kopalle, Katherine L. Rothamel, Xuezhen Ge, Elle Epstein, Orel Mizrahi, Assael A. Madrigal, Hsuan-Lin Her, Trent A. Gomberg, Anita Hermann, Joshua L Schwartz, Amanda J. Daniels, U. Manor, J. Ravits, R. Signer, Eric J. Bennett, Gene W. Yeo   +17 more
semanticscholar   +1 more source