Results 51 to 60 of about 204,995 (279)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Effect of aripiprazole on mismatch negativity (MMN) in schizophrenia. [PDF]
PLoS ONE, 2013 BACKGROUND: Cognitive deficits are considered core symptoms of the schizophrenia. Cognitive function has been found to be a better predictor of functional outcome than symptom levels.
Zhenhe Zhou, Hongmei Zhu, Lin Chen
doaj +1 more source
Sensory auditory processing and intuitive sound detection : an investigation of musical experts and nonexperts [PDF]
, 2006 The auditory system can detect occasional changes (deviants) in acoustic regularities without the need for subjects to focus their attention on the sound material.
van Zuijen, Titia
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Modelling trial-by-trial changes in the mismatch negativity.
PLoS Computational Biology, 2013 The mismatch negativity (MMN) is a differential brain response to violations of learned regularities. It has been used to demonstrate that the brain learns the statistical structure of its environment and predicts future sensory inputs.
Falk Lieder +4 more
doaj +1 more source
Event-related potential studies of somatosensory detection and discrimination. [PDF]
, 2007 This thesis contains four studies, the first examining methodology issues and four subsequent ones examining somatosensory cortical processing using event-related potentials (ERPs). The methodology section consists of 2 experiments.
Spackman, L.
core
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Aplicabilidade do Mismatch Negativity na população infantil: revisão sistemática de literatura
Audiology: Communication Research, 2017 RESUMO Introdução Mismatch Negativity (MMN) é um potencial eletrofisiológico que mede a habilidade do cérebro em discriminar sons, independente da capacidade atencional e comportamental.
Dulce Azevedo Ferreira +3 more
doaj +1 more source
Duration Mismatch Negativity Predicts Remission in First-Episode Schizophrenia Patients
Frontiers in Psychiatry, 2021 Objective: Remission in schizophrenia patients is associated with neurocognitive, social, and role functioning during both the early and chronic stages of schizophrenia.
Suguru Nakajima +14 more
doaj +1 more source