Results 41 to 50 of about 607,299 (306)

A mixed-methods systematic review of the prevalence, reasons, associated harms and risk-reduction interventions of over-the-counter (OTC) medicines misuse, abuse and dependence in adults

Journal of Pharmaceutical Policy and Practice, 2021
Background Over-the-counter (OTC) medicines are typically safe. However, there is evidence that OTC medicines can sometimes cause harm as a result of their misuse, abuse and dependence.
Mohammad Algarni, Muhammad Abdul Hadi, Asma Yahyouche, Sajid Mahmood, Zahraa Jalal   +4 more
doaj   +1 more source

Non-medical Use of Prescription Gabapentinoids (Gabapentin and Pregabalin) in Five European Countries

Frontiers in Psychiatry, 2021
Background: Non-medical use (NMU) of prescription GABA analogs (pregabalin and gabapentin) has been reported especially in opiate dependent persons.
Francina Fonseca, Francina Fonseca, Francina Fonseca, William Lenahan, Richard C. Dart, Esther Papaseit, Esther Papaseit, Paul I. Dargan, Paul I. Dargan, David M. Wood, David M. Wood, Marilena Guareschi, Icro Maremmani, Marc Auriacombe, Marc Auriacombe, Marc Auriacombe, Magí Farré, Magí Farré, Norbert Scherbaum, Marta Torrens, Marta Torrens, Marta Torrens   +21 more
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Misuse of Respiratory Inhalers Among Hospitalized Patients in a Tertiary Health Care Hospital in Kabul

International Journal of COPD, 2023
Ershad Ahmad Mushkani,1 Fahima Hamidy,2 Tawfiq Ahmad,3 Mohammad Asef Adelyar4 1Department of Pharmacology, Kabul University of Medical Sciences, Kabul, Afghanistan; 2Department of Nursing Skills, Aliabad Teaching Hospital, Kabul University of Medical ...
Mushkani EA, Hamidy F, Ahmad T, Adelyar MA   +3 more
doaj  

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Improving patient experience for people prescribed medicines with a risk of dependence or withdrawal: co-designed solutions using experience based co-design

BMC Primary Care
Background Significant concerns have been raised regarding how medications with a risk of dependence or withdrawal are managed and how care is experienced by patients.
Jennifer Seddon, Claire Friedrich, Sarah Wadd, David Dicks, Sion Scott, Anthea Robinson, Charlotte Walker   +6 more
doaj   +1 more source

Social and Cultural Contexts of Alcohol Use: Influences in a Social-Ecological Framework. [PDF]

, 2016
Alcohol use and misuse account for 3.3 million deaths every year, or 6 percent of all deaths worldwide. The harmful effects of alcohol misuse are far reaching and range from individual health risks, morbidity, and mortality to consequences for family ...
Sudhinaraset, May, Takeuchi, David T, Wigglesworth, Christina   +2 more
core   +1 more source

Misuse of dothiepin [PDF]

BMJ, 1995
EDITOR,--Recently we have become aware of a considerable population of intravenous drug misusers in the Greater Dublin area who are misusing the tricyclic antidepressant dothiepin (Prothiaden). The Drug Treatment Centre, Dublin, runs an evening programme of low dose methadone maintenance and harm reduction with needle exchange and health promotion ...
A, Dorman, D, Talbot, P, Byrne, J, O'Connor   +3 more
openaire   +2 more sources

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, EarlyView.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source