Results 111 to 120 of about 218,215 (277)

Building Strong User Experiences in LibGuides with Bootstrapr and Reviewr

open access: yesCode4Lib Journal, 2020
With nearly fifty subject librarians creating LibGuides, the LibGuides Management Team at Notre Dame needed a way to both empower guide authors to take advantage of the powerful functionality afforded by the Bootstrap framework native to LibGuides, and ...
Randal Sean Harrison
doaj  

“I'll still kick your ass even in my skirt”.

open access: yesBabylonia, 2021
In diesem Beitrag stellen wir dar, wie Schüler*innen der Sekundarstufe II (3. Schuljahr) sich im Fach Englisch vertieft mit der Darstellung von Feminismus in selbst ausgewählten Musikvideos auseinandergesetzt haben.
Elke Schlote   +3 more
doaj  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

A Typed Language for Truthful One-Dimensional Mechanism Design [PDF]

open access: yes, 2008
We first introduce a very simple typed language for expressing allocation algorithms that allows automatic verification that an algorithm is monotonic and therefore truthful.
Lapets, Andrei   +2 more
core   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

Zur Entwicklung eines interaktiven Verfahrens der Sprachstandsermittlung bei mehrsprachig aufwachsenden Kindern – von der Idee zu ersten Umsetzungsschritten

open access: yesZeitschrift für Interkulturellen Fremdsprachenunterricht, 2016
Dieser Beitrag skizziert ein Konzept zur Sprachstandsermittlung, das aufbauend auf Ergebnissen der gebrauchsbasierten Spracherwerbsforschung die sprachlichen Fähigkeiten von Vorschulkindern in quasi-natürlichen Gesprächssituationen misst.
Jörg Roche et al.
doaj  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard   +8 more
wiley   +1 more source

Mollier h-x diagram (Web App): An open-source browser-based psychrometric calculator

open access: yesSoftwareX
Psychrometric charts are essential in HVAC design and education, but manual look-ups and spreadsheet workflows are slow and error-prone. This paper presents the Mollier h-x Diagram Web App, an open-source browser-based tool that performs fast ...
Kenneth Bisgaard Christensen
doaj   +1 more source

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