Results 201 to 210 of about 218,215 (277)

Motivationales Scaffolding mit Learning-App

open access: yes
Die vorliegende empirische Studie konzentriert sich auf den Einsatz von Scaffolding, das durch eine Learning-App zur Anwendung kommt. Das primäre Ziel war es zu überprüfen, ob sich der Wissenserwerb durch den Einsatz spezifischer Prompts steigert. Im Rahmen dieser Studie wird Scaffolding als eine Form der didaktischen Unterstützung definiert, die es ...
openaire   +1 more source

Hub genes and diagnostic model associated with mitochondrial function in Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and mitochondrial dysfunction has been confirmed in AD patients and mouse models. However, the pathogenic genes associated with AD and early diagnostic methods based on mitochondrial function remain to be explored.
Xuchao Zhu, Ling Zhang, Chuan Qin
wiley   +1 more source

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan   +2 more
wiley   +1 more source

[Telemonitoring for chronically ill patients with multimorbidity is technically feasible!] [PDF]

open access: yesGesundheitswesen
Dohmen S   +10 more
europepmc   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie   +4 more
wiley   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud   +3 more
wiley   +1 more source

Building Molecules by a Self‐Replicator That Catalyzes Acyl Hydrazone Formation

open access: yesAngewandte Chemie, EarlyView.
A self‐replicator efficiently catalyzes the formation of acyl hydrazone bonds between a set of different substrates. In addition to previously reported (bond‐breaking) catalytic activity, this renders the self‐replicator highly promiscuous, which is a good starting point for Darwinian experiments en route to de‐novo life.
Kayleigh S. van Esterik   +2 more
wiley   +2 more sources

Bayesian Mixed Models Approach to Exploring Resilience: Impact of Stress on Subjective Health and Affects Over Time During the COVID-19 Pandemic. [PDF]

open access: yesInt J Methods Psychiatr Res
Schepers M   +10 more
europepmc   +1 more source

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