Results 81 to 90 of about 255,261 (219)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Wind-induced vibration control of bridge girders by aerodynamic and mechanical methods: a literature review

Advances in Bridge Engineering
Wind-induced vibration (WIV) is an essential factor in the safety and serviceability of long-span bridges, and aerodynamic and mechanical methods are two main countermeasures for WIV control of bridge girders.
Zheng Lu, Sheng Li, Jundong Fu, Qi Li, Zhao-Dong Xu   +4 more
doaj   +1 more source

Causes of the Outer Spiral Rainbands in Typhoon Yagi （ 2018） in Shandong Province of China

Gaoyuan qixiang
On August 14， 2018， Typhoon Yagi （2018） moved northward and impacted Shandong Province of China， resulting in widespread rainstorm and heavy rainstorm.The total rainfall caused by the typhoon in Shandong presents a round-shaped distribution.Specifically，
Chunyan SHENG, Sudan FAN, Qiaona QU, Shijun LIU, Wengang ZHU   +4 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Dynamic mechanical response of unsaturated beach sand under confined one-dimensional compression

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
This study investigates the dynamic mechanical behavior of unsaturated beach sand under high-strain-rate loading (300–1000 s⁻1) using a modified Split-Hopkinson Pressure Bar (SHPB) system with passive confinement.
Jian’an Wu, Linjian Ma, Hansheng Geng, Yuetang Zhao, Zeng Li, Jicheng Liu, Lu Dong   +6 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Opportunities and Challenges Faced by the Basic Marine Ecological Early Warning Monitoring Institutions

Haiyang Kaifa yu guanli
With the intensification of global climate change and the increasing frequency of human marine activities, the marine ecosystem is facing unprecedented pressure.
LIU Xinjie, LIU Liang, XU Yushan, ZHANG Xinxin, LI Ying   +4 more
doaj  

Automated Generation of Geometric FE Models for Timber Structures Using 3D Point Cloud Data

Buildings
Manual geometric modeling of timber structures is time-intensive and error-prone, impeding efficient structural analysis. To overcome this limitation, this study develops an automated framework for the rapid generation of 3D geometric finite element (FE)
Lin Chen, Liufang Jiang, Haibei Xiong
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source