Results 71 to 80 of about 4,851,512 (253)

URBAN INDIA AND CLIMATE CHANGE: MITIGATION STRATEGIES TOWARDS INCLUSIVE GROWTH [PDF]

Climate change has been emerged as a major challenge for the sustainable human settlement. The recent studies have established scientific evidences for climate change.
Sohail AHMAD, Mack Joong CHOI
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Inter-Temporal Investment in Climate Change Adaptation and Mitigation [PDF]

Currently, different dimensions of mitigation strategies have been investigated in policy analysis. However, ambitious mitigation action aiming at reducing future climate change will not prevent much climate change before mid-century.
McCarl, Bruce A., Wang, Weiwei
core  

Reduction of methane emission from landfills using bio-mitigation systems – from lab tests to full scale implementation [PDF]

, 2014
Landfills are significant sources of methane, which contributes to climate change. As an alternative to mitigation by gas utilization systems, bio-mitigation systems may be implemented.
Kjeldsen, Peter, Scheutz, Charlotte
core  

Adaptation and Mitigation Strategies of Climate Change from Agricultural Sector in the Tabalong District (South Borneo)

Jurnal Sosial Humaniora
Agriculture and climate change have a complex causal relationship. The agricultural sector produces large amounts of Green House Gases (GHG) such as CH4, CO2, and N2O which affect the climate.
Rian Yaitsar Chaniago, Rachmat Boedisantoso, Arie Dipareza Syafei   +2 more
doaj  

Attitudes and Behaviours Regarding COVID‐19 Mitigation Strategies in Australians With an Underlying Health Condition: A Cross‐Sectional Study

Health Expectations
Background Public health strategies have focused on preventing and slowing the transmission of COVID‐19 by promoting the uptake of mitigation strategies.
Sze‐Ee Soh, Darshini Ayton, Amelia Bevins, Helen Skouteris, Mallory Trent, Raina MacIntyre   +5 more
doaj   +1 more source

The outbreak of Drupella snails and its catastrophic effects on coral reefs: a comprehensive review

Frontiers in Marine Science
The recurring outbreaks of Drupella snails are a significant threat to coral reef ecosystems on a global scale. However, research on Drupella snails is currently very fragmentary.
Fang Zhang, Fang Zhang, Xiwang Jia, Zhenni Lin, Yiyi Jiang, Yiyi Jiang, Mengjie Qu, Mengjie Qu, Mengjie Qu   +8 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Economics analysis of mitigation strategies for FMD introduction in highly concentrated animal feeding regions [PDF]

Outbreaks of infectious animal diseases can lead to substantial losses as evidenced by 2003 US BSE (Bovine Spongiform Encephalopathy) event with consequent loss of export markets, and the 2001 UK FMD (Foot and Mouth Disease) outbreak that has cost ...
Elbakidze, Levan, Norby, Bo, McCarl, Bruce A., Ward, Michael P., Highfield, Linda   +4 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source