Results 121 to 130 of about 2,143,132 (361)
PLoS ONE, 2014 Exposure to bisphenol A (BPA), a monomer widely used to manufacture polycarbonate plastics, has been reported to be associated with abnormalities of liver function and hepatic damage.
W. Xia +11 more
semanticscholar +1 more source
Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]
, 2010 Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M. +7 more
core +2 more sources
Advanced Functional Materials, EarlyView.This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Impact of mitochondrial lipid alterations on liver disease mechanisms and progression
Exploration of Digestive DiseasesLipids are intricate biomolecules responsible for the building up of biological membranes. Besides this structural function, they also display crucial roles in signaling, acting as second messengers that activate specific pathways.
Laura Fàbrega +3 more
doaj +1 more source
MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY [PDF]
Journal of Veterinary and Animal Sciences, 1994 Ultrastructural changes of renal and hepatic mitochondria in mice induced by OA were studied. Mitrochondria exhibited diverse morphological aberrations. The outer mitochondria) membranes, cristae and matrix were affected. The changes were more prominent
N. Divakaran Nair +3 more
doaj
Бюллетень сибирской медицины, 2009 The influence of hepatoprotector phospholipid nature Essentiale and Essenciale combination with succinic acid on the metabolism of liver injury caused by Paracetamol in rats has been investigated.
D. A. Korshunov
doaj +1 more source
Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Experimental and Molecular Medicine, 2019 Liver injury: Citrus peel to the rescue Nobiletin, an antioxidant found in citrus peel, may protect the liver from reperfusion injury, damage following blood flow interruption.
Theodomir Dusabimana +4 more
doaj +1 more source
Role of the Mitochondrial Genome During Early Development in Mice [PDF]
, 1973 The role of the mitochondrial genome in early development and differentiation was studied in mouse embryos cultured in vitro from the two to four cell stage to the blastocyst (about 100 cells).
Chase, David G., Pikó, Lajos
core
Advanced Functional Materials, EarlyView.The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source