Results 181 to 190 of about 1,007,169 (424)
A quantitative study on the growth variability of tumour cell clones in vitro [PDF]
Objectives: In this study, we quantify the growth variability of tumour cell clones from a human leukemia cell line. Materials and methods: We have used microplate spectrophotometry to measure the growth kinetics of hundreds of individual cell clones from the Molt3 cell line.
arxiv
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat [PDF]
Superoxide is the proximal reactive oxygen species (ROS) produced by the mitochondrial respiratory chain and plays a major role in pathological oxidative stress and redox signaling.
Aksentijević, Dunja+13 more
core +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie+8 more
wiley +1 more source
Clustering and spatial distribution of mitochondria in dendritic trees [PDF]
Neuronal dendrites form densely branched tree architectures through which mitochondria must be distributed to supply the cell's energetic needs. Dendritic mitochondria circulate through the tree, undergoing fusion and fission to form clusters of varying sizes.
arxiv
CYTOCHEMICAL STUDIES OF MITOCHONDRIA [PDF]
Philip Siekevitz, Michael L. Watson
openalex +1 more source
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
THE DISTRIBUTION OF HISTOCHEMICALLY DEMONSTRABLE SUCCINIC DEHYDROGENASE AND OF MITOCHONDRIA IN TONGUE AND SKELETAL MUSCLES [PDF]
M. Wachstein, E. Meisel
openalex +1 more source
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan+11 more
wiley +1 more source
Summary: Bisphenol S (BPS) exposure has been implied epidemiologically to increase obesity risk, but the underlying mechanism is unclear. Here, we propose that BPS exposure at an environmentally relevant dose aggravates diet-induced obesity in female ...
Xue Wen+8 more
doaj
Effect of Synthetic Detergents on the Swelling and the ATPase of Mitochondria Isolated from Rat Liver [PDF]
Robert F. Witter, William Mink
openalex +1 more source