Results 181 to 190 of about 916,375 (359)
Advanced Materials, EarlyView.Microarchitecture sculpting via phase separation programs hydrogel mechanics by creating globular, inverse globular, and spinodal structures. Spinodal architectures deliver superior toughness and energy dissipation, while ionic modulation through single polymer phase separation offers a simple, scalable route to tune mechanical properties ...
Castro Johnbosco +9 more
wiley +1 more source
Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma
Advanced Materials, EarlyView.A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li +11 more
wiley +1 more source
Advanced Materials, EarlyView.Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu +11 more
wiley +1 more source
Fruit fly mitochondria switch fuel when the going gets hot [PDF]
, 2021 Kathryn Knight
openalex +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Advanced Materials, EarlyView.Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
Astrocytes donate mitochondria to increase glioblastoma tumorigenicity [PDF]
, 2021 Justin D. Lathia +10 more
openalex +1 more source
Advanced Materials Interfaces, EarlyView.Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing +5 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó +4 more
wiley +1 more source
A central role for PINK1 in governing local mitochondrial biogenesis and degradation in neurons. [PDF]
Cell Mol Life SciHelms M, Harbauer AB.
europepmc +1 more source