Results 311 to 320 of about 1,007,169 (424)

Applying Ultrasound to Mechanically and Noninvasively Sensitize Prostate Tumors to TRAIL‐Mediated Apoptosis

open access: yesAdvanced Science, EarlyView.
This study explores the application of therapeutic, focal ultrasound to noninvasively enhance the anti‐cancer effects of Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) as a targeted treatment for prostate cancer. This is achieved by mechanically activating mechanosensitive ion channels within cancer cells.
Abigail R. Fabiano   +10 more
wiley   +1 more source

METABOLIC STUDIES ON HEART MITOCHONDRIA

open access: hybrid, 1956
Carmel M. Montgomery, J. Webb
openalex   +1 more source

The Origin and Diversification of Mitochondria

open access: yesCurrent Biology, 2017
A. Roger   +2 more
semanticscholar   +1 more source

Squamocin Suppresses Tumor Growth through Triggering an Endoplasmic Reticulum Stress‐Associated Degradation of EZH2/MYC Axis

open access: yesAdvanced Science, EarlyView.
Squamocin disrupts mitochondrial respiratory Complex I function, reduces ATP production, and impairs HSP90α function, provoking endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in multiple cancer tumor models cell lines and in vivo tumor models.
Yin Zhu   +9 more
wiley   +1 more source

Targeted mitochondrial therapy for pancreatic cancer. [PDF]

open access: yesTransl Oncol
Zhao X, Wu G, Tao X, Dong D, Liu J.
europepmc   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

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