Results 81 to 90 of about 591,098 (317)

Synthesis of cytochrome oxidase components in isolated mitochondria of Neurospora crassa [PDF]

, 1974
The formation of polypeptides within the mitochondrion has been documented by a large body of evidence.
Walter Neupert, Ruecker, Axel Von, Axel Von Ruecker, Neupert, Walter, Axe Von Ruecker, Rücker, Axel von, Werner, Sigurd, Sigurd Werner   +7 more
core   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Cyclic AMP Receptor Protein from Yeast Mitochondria [PDF]

, 1985
We have identified and characterized a cyclic AMP receptor protein in mitochondria of the yeast Saccharomyces cerevisiae. The binding is specific for cyclic nucleotides, particularly for cyclic AMP which is bound with high affinity (Kd of 10(-9) M) at 1 ...
Rödel, Gerhard, Bandlow, Wolfhard, Müller, Günter   +2 more
core  

Non-chemical Signalling Between Mitochondria [PDF]

, 2023
A wide variety of studies have reported some form of non-chemical or non-aqueous communication between physically isolated organisms, eliciting changes in cellular proliferation, morphology, and/or metabolism.
Nunn, A., Thomas, E.L., Mould, R., Guy, G., Bell, J.D., Kalampouka, I.   +5 more
core   +1 more source

Hydroxysafflor yellow A ameliorates depression-like behavior in Parkinson's disease mice

Pakistan Journal of Pharmaceutical Sciences
Depression is a common non-motor symptom of Parkinson’s disease. Previous studies demonstrated that hydroxysafflor yellow A had properties of improving motor symptoms of Parkinson’s disease.
Huilin Zhang, Xiaohan Zhang, Xue Jia, Wei Zheng, Jie He, Zhenhua Wang, Tian Wang, Bing Han   +7 more
doaj   +1 more source

Evolution of Physical Status From Diagnosis to the End of First-Line Treatment in Breast, Lung, and Colorectal Cancer Patients: The PROTECT-01 Cohort Study Protocol

Frontiers in Oncology, 2020
Background: Cancer cachexia and exacerbated fatigue represent two hallmarks in cancer patients, negatively impacting their exercise tolerance and ultimately their quality of life.
Joris Mallard, Joris Mallard, Elyse Hucteau, Elyse Hucteau, Roland Schott, Thierry Petit, Martin Demarchi, Christine Belletier, Meher Ben Abdelghani, Hélène Carinato, Pascale Chiappa, Cathie Fischbach, Michal Kalish-Weindling, Audren Bousinière, Stéphane Dufour, Fabrice Favret, Xavier Pivot, Thomas J. Hureau, Allan F. Pagano   +18 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

APOOL is a cardiolipin-binding component of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria [PDF]

, 2013
Mitochondrial cristae morphology is highly variable and altered under numerous pathological conditions. The protein complexes involved are largely unknown or only insufficiently characterized.
Michel Mittelbronn, Alexander van der Bliek, Sebastian Koob, Head, Brian, Wittig, I., Reichert, A.S., Brandt, Ulrich, Heide, H., Bliek, A. van der, Reichert, Andreas, Bliek, Alexander van der, Tobias A Weber, Weber, Tobias Alexander, Brandt, U., Mittelbronn, Michel Guy André, Brian Head, Koob, Sebastian, Heide, Heinrich, Head, B., Koob, S., Ulrich Brandt, Ilka Wittig, Wittig, Ilka, Andreas S Reichert, Heinrich Heide, Weber, T.A., Mittelbronn, M.   +26 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo [PDF]

, 1991
With vital yeast cells, a hybrid protein consisting of the amino- terminal third of the precursor to cytochrome b2 and of the entire dihydrofolate reductase was arrested on the import pathway into mitochondria.
W Neupert, M Schleyer, Pfanner, Nikolaus, Schleyer, Manfred, Neupert, Walter, Horwich, Arthur, B Guiard, Guiard, Bernard, N Pfanner, Wienhues, Ulla, K Becker, A L Horwich, Tropschug, Maximilian, Becker, Karin, U Wienhues, M Tropschug   +15 more
core   +1 more source