Results 71 to 80 of about 902,846 (308)
MoleculesDianthus superbus L. has been extensively studied for its potential medicinal properties in traditional Chinese medicine and is often consumed as a tea by traditional folk.
Zikai Lin +7 more
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Role of Mitochondria in Ferroptosis
Molecules and Cells, 2018 Summary Ferroptosis is a regulated necrosis process driven by iron-dependent lipid peroxidation. Although ferroptosis and cellular metabolism interplay with each other, whether mitochondria are involved in ferroptosis is under debate. Here we demonstrate
Minghui Gao +6 more
semanticscholar +1 more source
Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances
Molecular Neurodegeneration, 2020 Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases, characterized by impaired cognitive function due to progressive loss of neurons in the brain.
Wenzhang Wang +4 more
semanticscholar +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Morphology of mitochondria and cell respiration,pt.1. [PDF]
, 1960 To reveal the mechanism of liver damage by taking CCl4 the author observed the liver tissues from rats at 1.5, 5, 6, 10, 17, 20, and 22 hours after the CCl4 administration, both by light microscope and electron-microscope. 1. Light microscope observation
Haba, Kyoichi
core +1 more source
Frontiers in Nutrition, 2022 Obesity is a significant health concern as a result of poor-quality diet, for example, high-fat diet (HFD). Although multiple biological and molecular changes have been identified to contribute to HFD-induced pain susceptibility, the mechanisms are not ...
Nan Lian +14 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Aberrant branched-chain amino acid catabolism in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2022 Globally, cardiovascular diseases are the leading cause of death. Research has focused on the metabolism of carbohydrates, fatty acids, and amino acids to improve the prognosis of cardiovascular diseases.
Yixiao Xiong +5 more
doaj +1 more source
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
PLoS Biology, 2010 Mutations in PINK1 or Parkin lead to familial parkinsonism. The authors suggest that PINK1 and Parkin form a pathway that senses damaged mitochondria and selectively targets them for degradation.
Derek P. Narendra +7 more
semanticscholar +1 more source
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
JCI Insight, 2020 Doxorubicin (DOX), a chemotherapeutic agent, induces a cardiotoxicity referred to as doxorubicin-induced cardiomyopathy (DIC). This cardiotoxicity often limits chemotherapy for malignancies and is associated with poor prognosis.
T. Tadokoro +11 more
semanticscholar +1 more source