Results 41 to 50 of about 142,742 (137)

Mitochondria-Targeted Drug Delivery

Pharmaceutics, 2022
Mitochondria, organelles surrounded by a double membrane and with their own small genome, are the cells’ energy centres [...]
Joanna Kopecka
doaj   +1 more source

Progress in mitochondrial epigenetics

Biomolecular Concepts, 2013
Mitochondria, intracellular organelles with their own genome, have been shown capable of interacting with epigenetic mechanisms in at least four different ways.
Manev Hari, Dzitoyeva Svetlana
doaj   +1 more source

Mitochondrial DNA Integrity: Role in Health and Disease

Cells, 2019
As the primary cellular location for respiration and energy production, mitochondria serve in a critical capacity to the cell. Yet, by virtue of this very function of respiration, mitochondria are subject to constant oxidative stress that can damage one ...
Priyanka Sharma, Harini Sampath
doaj   +1 more source

A simplified method to isolate rice mitochondria

Plant Methods, 2020
Background Mitochondria play critical roles in plant growth, development and stress tolerance. Numerous researchers have carried out studies on the plant mitochondrial genome structure, mitochondrial metabolism and nuclear-cytoplasmic interactions ...
Yanghong Xu, Xiaoyi Li, Jishuai Huang, Leilei Peng, Dinghui Luo, Qiannan Zhang, Zhiwu Dan, Haijun Xiao, Fang Yang, Jun Hu   +9 more
doaj   +1 more source

Enzymes involved in organellar DNA replication in photosynthetic eukaryotes

Frontiers in Plant Science, 2014
Plastids and mitochondria possess their own genomes. Although the replication mechanisms of these organellar genomes remain unclear in photosynthetic eukaryotes, several organelle-localized enzymes related to genome replication, including DNA polymerase,
Takashi eMoriyama, Takashi eMoriyama, Naoki eSato, Naoki eSato   +3 more
doaj   +1 more source

Mitochondrial Tethers and Their Impact on Lifespan in Budding Yeast

Frontiers in Cell and Developmental Biology, 2018
Tethers that link mitochondria to other organelles are critical for lipid and calcium transport as well as mitochondrial genome replication and fission of the organelle.
Wolfgang M. Pernice, Theresa C. Swayne, Istvan R. Boldogh, Liza A. Pon, Liza A. Pon   +4 more
doaj   +1 more source

Mitochondria in Health and Disease

Cells, 2019
Mitochondria are best known as the sites for production of respiratory ATP and are essential for eukaryotic life. They have their own genome but the great majority of the mitochondrial proteins are encoded by the nuclear genome and are imported into the ...
Sarah J. Annesley, Paul R. Fisher
doaj   +1 more source

Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c

Molecular & Cellular Oncology, 2019
Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors.
Changhan Lee
doaj   +1 more source

Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.

PLoS ONE, 2015
To date, mitochondrial DNA polymerase γ (POLG) is the only polymerase known to be present in mammalian mitochondria. A dogma in the mitochondria field is that there is no other polymerase present in the mitochondria of mammalian cells.
Bhupendra Singh, Xiurong Li, Kjerstin M Owens, Ayyasamy Vanniarajan, Ping Liang, Keshav K Singh   +5 more
doaj   +1 more source

Human mitochondria and mitochondrial genome function as a single dynamic cellular unit. [PDF]

, 1994
Jun-Ichi Hayashi, Masakazu Takemitsu, Y. Goto, Ikuya Nonaka   +3 more
openalex   +1 more source