Results 61 to 70 of about 2,539,821 (192)
Transport of proteins into mitochondria [PDF]
, 1985 Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core +1 more source
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Cell, 2020 Mitochondria, which play central roles in immunometabolic diseases, have their own genome. However, the functions of mitochondria-located noncoding RNAs are largely unknown due to the absence of a specific delivery system.
Qi-Yi Zhao +12 more
semanticscholar +1 more source
Genes of mitochondrial origin in the genus Entamoeba [PDF]
, 2002 Entamoeba histolytica is the protozoan parasite that causes amoebic dysentery and amoebic liver abscesses in humans. For many years it was believed to be a primitive organism because it lacks many typical eukaryotic features including mitochondria ...
Bakatselou, Christina
core +1 more source
The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus
Memorias do Instituto Oswaldo Cruz, 2016 We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of high-throughput and Sanger sequencing ...
James L Crainey +5 more
doaj +1 more source
Mutation of mitochondria genome: trigger of somatic cell transforming to cancer cell
International Archives of Medicine, 2010 Nearly 80 years ago, scientist Otto Warburg originated a hypothesis that the cause of cancer is primarily a defect in energy metabolism. Following studies showed that mitochondria impact carcinogenesis to remodel somatic cells to cancer cells through ...
Jian-Ping Du
semanticscholar +1 more source
The role of mitochondria in rheumatic diseases
Nature Reviews Rheumatology, 2022 The mitochondrion is an intracellular organelle thought to originate from endosymbiosis between an ancestral eukaryotic cell and an α-proteobacterium. Mitochondria are the powerhouses of the cell, and can control several important processes within the ...
Y. Becker +4 more
semanticscholar +1 more source
Mitochondria and G-quadruplex evolution: An intertwined relationship
Trends in Genetics, 2022 G-quadruplexes (G4s) are non-canonical structures formed in guanine-rich sequences through stacked guanine tetrads by Hoogsteen hydrogen bonding. Several studies have demonstrated the existence of G4s in the genome of various organisms, including humans,
V. Sahayasheela +4 more
semanticscholar +1 more source
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert +5 more
core +2 more sources
Cell Metabolism, 2020 SUMMARY Recent studies suggest that mitochondria can be transferred between cells to support the survival of metabolically compromised cells. However, whether intercellular mitochondria transfer occurs in white adipose tissue (WAT) or regulates metabolic
J. Brestoff +24 more
semanticscholar +1 more source
An Epigenetic Role of Mitochondria in Cancer
, 2022 Mitochondria are not only the main energy supplier but are also the cell metabolic center regulating multiple key metaborates that play pivotal roles in epigenetics regulation.
Sun, Yihong +13 more
core +1 more source