The consequences of nuclear transfer for mammalian foetal development and offspring survival : a mitochondrial DNA perspective [PDF]
Review of the articleThe introduction of nuclear transfer (NT) and other technologies that involve embryo reconstruction require us to reinvestigate patterns of mitochondrial DNA (mtDNA) transmission, transcription and replication.
Anderson +80 more
core +1 more source
The complete mitochondrial genome of Yarrowia lipolytica [PDF]
We here report the complete nucleotide sequence of the 47.9 kb mitochondrial (mt) genome from the obligate aerobic yeast Yarrowia lipolytica.
Brandt, Ulrich +4 more
core
How proteins are transported into mitochondria [PDF]
Most mitochondrial polypeptides are synthesized outside the organelle as precursors which are usually larger than the ‘mature’ polypeptides found within mitochondria.
Neupert, Walter, Schatz, Gottfried
core +1 more source
Progress in mitochondrial epigenetics
Mitochondria, intracellular organelles with their own genome, have been shown capable of interacting with epigenetic mechanisms in at least four different ways.
Manev Hari, Dzitoyeva Svetlana
doaj +1 more source
Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant? [PDF]
The expansion of genome sequencing projects has produced accumulating evidence for lateral transfer of genes between prokaryotic and eukaryotic genomes. However, it remains controversial whether these genes are of functional importance in their recipient
Vera ID Ros +17 more
core +2 more sources
LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux [PDF]
HIGHLIGHTS \u2022 Monovalent cation homeostasis is dysregulated upon LETM1 depletion \u2022 K+/H+ exchange activity is decreased in LETM1 knockdown cells \u2022 LETM1 depletion results in K+ accumulation in the mitochondrial matrix \u2022 LETM1 knockdown
Andrea Mattarei +8 more
core +3 more sources
Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport [PDF]
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)2bpy]Cl3 (phi is 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to ...
Barton, Jacqueline K. +2 more
core +2 more sources
The Mitochondrial Genome of the Hemichordate Balanoglossus carnosus and the Evolution of Deuterostome Mitochondria [PDF]
Abstract The complete nucleotide sequence of the mitochondrial genome of the hemichordate Balanoglossus carnosus (acorn worm) was determined. The arrangement of the genes encoding 13 protein, 22 tRNA, and 2 rRNA genes is essentially the same as in vertebrates, indicating that the vertebrate and hemichordate mitochondrial gene arrangement
Castresana, J. +4 more
openaire +3 more sources
Mitochondrial DNA Integrity: Role in Health and Disease
As the primary cellular location for respiration and energy production, mitochondria serve in a critical capacity to the cell. Yet, by virtue of this very function of respiration, mitochondria are subject to constant oxidative stress that can damage one ...
Priyanka Sharma, Harini Sampath
doaj +1 more source
Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. [PDF]
A small RNA encoded within the nucleus is an essential subunit of a RNA processing endonuclease (RNase MRP) hypothesized to generate primers for mitochondrial DNA replication from the heavy strand origin of replication.
Gonzalez, M +6 more
core

