Results 71 to 80 of about 2,539,821 (192)

DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology

Scientific Reports, 2017
Here we demonstrate localization of the isoform3 of DNA Methyltransferase1 (DNMT1) enzyme to mitochondria, instead of isoform1 as reported earlier. The fused DNMT1-isoform1, reported earlier to localize in mitochondria, surprisingly showed its exclusive ...
Sunil Kumar Saini, Kailash Chandra Mangalhara, Gopinath Prakasam, R. N. K. Bamezai   +3 more
doaj   +1 more source

Genome-Wide Localization Study of Yeast Pex11 Identifies Peroxisome–Mitochondria Interactions through the ERMES Complex

Journal of Molecular Biology, 2015
Pex11 is a peroxin that regulates the number of peroxisomes in eukaryotic cells. Recently, it was found that a mutation in one of the three mammalian paralogs, PEX11β, results in a neurological disorder.
M. M. Usaj, M. Brložnik, P. Kaferle, M. Zitnik, H. Wolinski, F. Leitner, S. Kohlwein, B. Zupan, U. Petrovič   +8 more
semanticscholar   +1 more source

Embryo and Its Mitochondria

Antioxidants, 2021
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute to many other essential cellular functions. One of the unique characteristics of the mitochondria is that they have their own genome, which is only maternally ...
P. May-Panloup, M. Boguenet, H. El Hachem, P. Bouet, P. Reynier   +4 more
semanticscholar   +1 more source

The SAR11 group of alpha-proteobacteria is not related to the origin of mitochondria.

PLoS ONE, 2012
Although free living, members of the successful SAR11 group of marine alpha-proteobacteria contain a very small and A+T rich genome, two features that are typical of mitochondria and related obligate intracellular parasites such as the Rickettsiales ...
Naiara Rodríguez-Ezpeleta, T Martin Embley   +1 more
doaj   +1 more source

Blood contains circulating cell‐free respiratory competent mitochondria

The FASEB Journal, 2020
Mitochondria are considered as the power‐generating units of the cell due to their key role in energy metabolism and cell signaling. However, mitochondrial components could be found in the extracellular space, as fragments or encapsulated in vesicles. In
Z. Al Amir Dache, A. Otandault, R. Tanos, B. Pastor, R. Meddeb, C. Sanchez, G. Arena, L. Lasorsa, A. Bennett, T. Grange, S. El Messaoudi, T. Mazard, C. Prévostel, A. Thierry   +13 more
semanticscholar   +1 more source

Morphology of mitochondria and cell respiration,pt.1. [PDF]

, 1960
To reveal the mechanism of liver damage by taking CCl4 the author observed the liver tissues from rats at 1.5, 5, 6, 10, 17, 20, and 22 hours after the CCl4 administration, both by light microscope and electron-microscope. 1. Light microscope observation
Haba, Kyoichi
core   +1 more source

ncRNAs: New Players in Mitochondrial Health and Disease?

Frontiers in Genetics, 2020
The regulation of mitochondrial proteome is unique in that its components have origins in both mitochondria and nucleus. With the development of OMICS technologies, emerging evidence indicates an interaction between mitochondria and nucleus based not ...
Mirjana Gusic, Mirjana Gusic, Mirjana Gusic, Holger Prokisch, Holger Prokisch   +4 more
doaj   +1 more source

Mitochondria Can Cross Cell Boundaries: An Overview of the Biological Relevance, Pathophysiological Implications and Therapeutic Perspectives of Intercellular Mitochondrial Transfer

International Journal of Molecular Sciences, 2021
Mitochondria are complex intracellular organelles traditionally identified as the powerhouses of eukaryotic cells due to their central role in bioenergetic metabolism.
D. Valenti, R. A. Vacca, L. Moro, A. Atlante   +3 more
semanticscholar   +1 more source

Progress in mitochondrial epigenetics

Biomolecular Concepts, 2013
Mitochondria, intracellular organelles with their own genome, have been shown capable of interacting with epigenetic mechanisms in at least four different ways.
Manev Hari, Dzitoyeva Svetlana
doaj   +1 more source

A Complex Genome-MicroRNA Interplay in Human Mitochondria

BioMed Research International, 2015
Small noncoding regulatory RNA exist in wide spectrum of organisms ranging from prokaryote bacteria to humans. In human, a systematic search for noncoding RNA is mainly limited to the nuclear and cytosolic compartments.
Santosh Shinde, U. Bhadra
semanticscholar   +1 more source