Results 121 to 130 of about 569,386 (218)

Molecular pathogenesis and gene therapy-based intervention of GTPBP3-related mitochondrial disease. [PDF]

Nat Commun
Zhang Y, Yao SY, Li J, Yu T, Liu H, Zhu N, Peng GX, Zheng WQ, Ma CR, Wang ED, Song C, Zhou XL.   +11 more
europepmc   +1 more source

Macrophage Membrane‐Camouflaged Nanozyme Microneedles Restore Immunovascular Homeostasis Through SPP1‐ApoE Signaling in Diabetic Wounds

Advanced Healthcare Materials, EarlyView.
Macrophage membrane‐coated Cu/Zn‐MOF nanozyme microneedles (MNs) reprogram the diabetic wound microenvironment through localized, minimally invasive delivery. By suppressing M1‐like macrophage activation while promoting extracellular matrix deposition and angiogenesis, this biomimetic platform accelerates diabetic wound repair.
Qipeng Wu, Yuan Xiong, Li Lu, Han Wang, Hui Hu, Mohammad‐Ali Shahbazi, Guohui Liu, Bobin Mi   +7 more
wiley   +1 more source

A step from the physiology to the physiome

Integrative Medicine Research, 2016
Akinori Noma, Jae Boum Youm
doaj   +1 more source

Neurological manifestations and genotype-phenotype correlations in <i>NDUFAF6</i>-associated mitochondrial disease. [PDF]

Brain Commun
Torraco A, Alston CL, Barcia G, Verrigni D, Rizza T, Di Nottia M, Altobelli A, Martinelli D, Diodato D, Efthymiou S, Kose M, Kriouile Y, Lim AZ, Morlino S, Siri B, Saadi NW, Novelli A, Houlden H, Dionisi-Vici C, McFarland R, Rötig A, Bertini E, Taylor RW, Carrozzo R.   +23 more
europepmc   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Loss of TMEM65 in mice causes mitochondrial disease mediated by mitochondrial Ca². [PDF]

Nat Commun
Zhang Y, Parry HA, Reyes L, Shamoun A, Sun J, Liu C, Springer D, Noguchi A, Nakamori S, Aponte AM, Munasinghe J, Covian R, Murphy E, Glancy B.   +13 more
europepmc   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

Commentary: Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease. [PDF]

Front Neurol
Finsterer J.
europepmc   +1 more source

Wearable OLED‐Assisted Photodynamic Cancer Therapy Using Chlorin e6‐Loaded Pluronic Nanocapsules as Photosensitizers

Advanced Healthcare Materials, EarlyView.
A novel photodynamic therapeutic approach has been employed for anticancer therapy, utilizing chlorin e6‐loaded Pluronic nanocapsules and a wearable organic light‐emitting diode light source. This has shown significant in vivo antitumor efficacy with minimal off‐target toxicity. The innovative combination of a wearable light source and photosensitizers
Hyeryeon Oh, Seung Min Jeong, Cheol Hui Park, Panmo Son, Yeseo Lee, Heebeom Koo, Won Il Choi, Kyung Cheol Choi   +7 more
wiley   +1 more source

Enrichment of Rare Mitochondrial DNA Variants Among Individuals With Kidney Disease Reveals Undiagnosed Mitochondrial Disease. [PDF]

Kidney Int Rep
Schecter DR, Tinker RJ, O'Connell P, Pang J, SzeKing Lee S, Kars ME, Guvenek A, Preuss M, Itan Y, Morava E, Kozicz T, Hirano M, Naini A, Ganesh J.   +13 more
europepmc   +1 more source