Results 141 to 150 of about 543,462 (281)

Role of Impaired Mitochondrial Dynamics Processes in the Pathogenesis of Alzheimer’s Disease [PDF]

, 2022
Alexander V. Blagov, Andrey V. Grechko, Nikita G. Nikiforov, Evgeny E. Borisov, Nikolay K. Sadykhov, Alexander N. Orekhov   +5 more
openalex   +1 more source

Mitochondrial disease

, 2004
Mitochondrial disorder, clinical features, investigation, genetics and treatment. The aim of this article is to give an overview of mitochondrial disorders. As my younger brother got this disease early in his childhood I have got a special interest in this disease.
openaire   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

New roles of LPGAT1: From mitochondrial import of phosphatidylglycerol to MEGDEL disease [PDF]

, 2023
Vera F. Monteiro-Cardoso, Francesca Giordano   +1 more
openalex   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Fontaine progeroid syndrome with neonatal mitochondrial disease. [PDF]

Hum Genome Var
Riko M, Kawamoto D, Hirayama K, Tsuchihashi T, Suzuki T, Sugimoto T, Okazaki Y, Murayama K, Tokuhara D.   +8 more
europepmc   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Bridging gaps in mitochondrial disease diagnosis: the role of advanced biomarker discovery. [PDF]

J Mol Med (Berl)
Makwikwi T, Schoonen M, Smuts I, van der Westhuizen FH.   +3 more
europepmc   +1 more source

Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer’s Disease

, 2014
Dongmei Wang, Ling Liu, Xiaoying Zhu, Wen‐Lan Wu, Yong Wang   +4 more
openalex   +2 more sources