Results 231 to 240 of about 533,276 (294)

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Family misfortune caused by hereditary bias: a reflection on mitochondrial disease diagnosis in a family. [PDF]

J Assist Reprod Genet
Meng Y, Wan L, Yang XY, Han F, Zhang MN, He W, Shi XY, Yang G, Zou LP, Hu LY.   +9 more
europepmc   +1 more source

Mechanisms of Disease: Is Mitochondrial Function Altered in Heart Failure?

, 2013
Dale J. Hamilton
openalex   +2 more sources

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Taurine supplementation improves physical activity level in a hemodialysis patient with mitochondrial disease: a case report. [PDF]

CEN Case Rep
Yoshida R, Mitsuno R, Nakayama T, Azegami T, Hashiguchi A, Torimitsu T, Yoshimoto N, Hisikawa A, Hagiwara A, Nakamura T, Meguro S, Katsumata M, Endo J, Matsunaga T, Yoshino J, Kanda T, Morimoto K, Monkawa T, Yoshida T, Nakahara J, Yamaguchi S, Hayashi K.   +21 more
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation. [PDF]

Brain
Smeitink J, van Es J, Bosman B, Janssen MCH, Klopstock T, Gorman G, Vissing J, Ruiterkamp G, Edgar CJ, Abbink EJ, van Maanen R, Pogoryelova O, Stendel C, Bischoff A, Karin I, Munshi M, Kümmel A, Burgert L, Verhaak C, Renkema H.   +19 more
europepmc   +1 more source

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells

, 2010
Oded Shaham, Nancy G. Slate, Olga Goldberger, Qiuwei Xu, Arvind Ramanathan, Amanda L. Souza, Clary B. Clish, Katherine B. Sims, Vamsi K. Mootha   +8 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Balancing Anesthesia in a Child With Mitochondrial Disease: A Case Report. [PDF]

Cureus
Manickam A, Fathima K, Bagri VA, Ganesh Prabu AVP, R VP.   +4 more
europepmc   +1 more source