Results 21 to 30 of about 9,815,793 (361)
Rescue of Heart Failure by Mitochondrial Recovery [PDF]
International Neurourology Journal, 2016 Heart failure (HF) is a multifactorial disease brought about by numerous, and oftentimes complex, etiological mechanisms. Although well studied, HF continues to affect millions of people worldwide and current treatments can only prevent further ...
Jubert Marquez +3 more
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Exercise and Neuroinflammation in Health and Disease [PDF]
International Neurourology Journal, 2019 Neuroinflammation is a central pathological feature of several acute and chronic brain diseases, including Alzheimer disease (AD), Parkinson disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).
Dae-Yun Seo +3 more
doaj +1 more source
Journal of Inherited Metabolic Disease, 2020 The aim of this study was to compare the value of serum biomarkers, fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15), with histological analysis of muscle in the diagnosis of mitochondrial disease.
Jenni M. Lehtonen +12 more
semanticscholar +1 more source
Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential
Molecular Neurodegeneration, 2023 Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease (PD). However, strategies aimed at ameliorating mitochondrial dysfunction, including antioxidants, antidiabetic drugs, and iron chelators, have
M. Henrich +3 more
semanticscholar +1 more source
FEBS Letters, 2020 The majority of proteins localised to mitochondria are encoded by the nuclear genome, with approximately 1500 proteins imported into mammalian mitochondria.
Catherine S Palmer +2 more
semanticscholar +1 more source
Indicators of mitochondrial disease [PDF]
Sao Paulo Medical Journal, 2013 In the article, the authors hypothesize that hepatosteatosis with unknown etiology presented by group of pediat-ric patients may be mitochondrial disease. They attribute their idea to mitochondrial structural abnormalities detected through electron microscopy examination.
Kurt, Yasemin Gulcan +3 more
openaire +8 more sources
Mitochondria as a Target for Future Diabetes Treatments
International Journal of Medical Students, 2015 Diabetes mellitus is rapidly becoming the world’s most dangerous serial killer. Type 1 diabetes (T1D) is a currently incurable autoimmune disease marked by progressive, and eventually exhaustive, destruction of the insulin-producing pancreatic beta cells.
Franziska Thimm, Marten Szibor
doaj +3 more sources
Ophthalmoplegia in Mitochondrial Disease [PDF]
Yonsei Medical Journal, 2018 To evaluate the classification, diagnosis, and natural course of ophthalmoplegia associated with mitochondrial disease.Among 372 patients with mitochondrial disease who visited our hospital between January 2006 and January 2016, 21 patients with ophthalmoplegia were retrospectively identified.
Ji Hoon Na +4 more
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Anesthetic considerations of Joubert syndrome in patients with mitochondrial disease - A case report - [PDF]
Anesthesia and Pain Medicine, 2021 Background Joubert syndrome and mitochondrial disease are rare congenital diseases in which a wide range of symptoms affects multiple organs. Patients with these diseases present characteristic symptoms related to the musculoskeletal, respiratory, and ...
Jeong Yeon Kim +5 more
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Mitochondrial Dynamics in Mitochondrial Diseases
Diseases, 2016 Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial network quality control.
Juan Suárez-Rivero +9 more
openaire +4 more sources