Results 31 to 40 of about 9,815,793 (361)

Mitochondrial heterogeneity in diseases

Signal Transduction and Targeted Therapy, 2023
AbstractAs key organelles involved in cellular metabolism, mitochondria frequently undergo adaptive changes in morphology, components and functions in response to various environmental stresses and cellular demands. Previous studies of mitochondria research have gradually evolved, from focusing on morphological change analysis to systematic multiomics,
Long Chen, Mengnan Zhou, Hao Li, Delin Liu, Peng Liao, Yao Zong, Changqing Zhang, Weiguo Zou, Junjie Gao   +8 more
openaire   +3 more sources

Morning and evening exercise

Integrative Medicine Research, 2013
A growing body of evidence suggests that exercise may contribute to preventing pathological changes, treating multiple chronic diseases, and reducing mortality and morbidity ratios.
Dae Yun Seo, SungRyul Lee, Nari Kim, Kyung Soo Ko, Byoung Doo Rhee, Byung Joo Park, Jin Han   +6 more
doaj   +1 more source

Pu-18-N-butylimide-NMGA-GNP conjugate is effective against hepatocellular carcinoma

Integrative Medicine Research, 2013
Background: Photodynamic therapy (PDT) is a new modality in the treatment of cancer. This study thus aims to examine whether the PDT is effective against in vivo hepatocellular carcinoma.
Jin-Geun Kwon, In-Sung Song, Min-Soo Kim, Beom Hee Lee, Jung Hwa Kim, Il Yoon, Young Key Shim, Nari Kim, Jin Han, Jae Boum Youm   +9 more
doaj   +1 more source

E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

Bioengineering & Translational Medicine, 2021
Recent studies indicate that umbilical cord stem cells are cytoprotective against several disorders. One critical limitation in using stem cells is reduction in their viability under stressful conditions, such as diabetes.
Ayaz Ali, Wei‐Wen Kuo, Chia‐Hua Kuo, Jeng‐Fan Lo, Michael Y. C. Chen, Jayasimha R. Daddam, Tsung‐Jung Ho, Vijaya Padma Viswanadha, Marthandam Asokan Shibu, Chih‐Yang Huang   +9 more
doaj   +1 more source

Mitochondrial TCA cycle metabolites control physiology and disease

Nature Communications, 2020
Mitochondria are signaling organelles that regulate a wide variety of cellular functions and can dictate cell fate. Multiple mechanisms contribute to communicate mitochondrial fitness to the rest of the cell.
I. Martínez-Reyes, N. Chandel
semanticscholar   +1 more source

Mitochondrial Disease and Anesthesia [PDF]

Journal of Inborn Errors of Metabolism and Screening, 2017
It is increasingly common for children with mitochondrial disease to undergo surgery and anesthesia. Although many different anesthetics have been used successfully for these patients, serious, unexpected complications have occurred during and following anesthetic exposure.
Hsieh, Vincent C., Krane, Elliot J., Morgan, Philip G.   +2 more
openaire   +5 more sources

Acetylcholinesterase Inhibitory Activity of Pigment Echinochrome A from Sea Urchin Scaphechinus mirabilis

Marine Drugs, 2014
Echinochrome A (EchA) is a dark-red pigment of the polyhydroxynaphthoquinone class isolated from sea urchin Scaphechinus mirabilis. Acetylcholinesterase (AChE) inhibitors are used in the treatment of various neuromuscular disorders, and are considered as
Sung Ryul Lee, Julius Ryan D. Pronto, Bolor-Erdene Sarankhuu, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han   +9 more
doaj   +1 more source

Quality Matters? The Involvement of Mitochondrial Quality Control in Cardiovascular Disease

Frontiers in Cell and Developmental Biology, 2021
Cardiovascular diseases are one of the leading causes of death and global health problems worldwide. Multiple factors are known to affect the cardiovascular system from lifestyles, genes, underlying comorbidities, and age.
Kai-Lieh Lin, Kai-Lieh Lin, Shang-Der Chen, Shang-Der Chen, Shang-Der Chen, Kai-Jung Lin, Chia-Wei Liou, Chia-Wei Liou, Chia-Wei Liou, Yao-Chung Chuang, Yao-Chung Chuang, Yao-Chung Chuang, Pei-Wen Wang, Pei-Wen Wang, Jiin-Haur Chuang, Jiin-Haur Chuang, Tsu-Kung Lin, Tsu-Kung Lin, Tsu-Kung Lin   +18 more
doaj   +1 more source

New diagnostic pathways for mitochondrial disease

, 2020
Mitochondrial diseases collectively represent the most common cause of inherited metabolic disease. They are estimated to affect at least 1 in 8,000 adults and at least 1 in 250 adults carry a disease-causing genetic mutation.
Eloise C. Watson, R. Davis, C. Sue
semanticscholar   +1 more source

Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs

Marine Drugs, 2014
Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong, Hyoung Kyu Kim, In-Sung Song, Seon Joong Lee, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoryev, Valentin A. Stonik, Jin Han   +10 more
doaj   +1 more source