Results 191 to 200 of about 920,301 (294)

In vivo tracking of transfused platelets by next-generation sequencing of mitochondrial DNA. [PDF]

Blood Adv
Choi SJ, Kwon SS, Kim HK, Suh EJ, Chung H, Cho H, Cheong JW, Kim S.   +7 more
europepmc   +1 more source

ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA

Huiyan Ji, Wanwan Jiang, Juan Zhang, Mengdi Liu, Danhua Su, Jiaxin Lei, Lingyi Li, Ming Zheng, Ting Liu, Zhichun Liu, Qinghua Cao, Lin Xu, Sidong Xiong, Zhenke Wen   +13 more
openalex   +2 more sources

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Mitochondrial DNA Replication and Disease: A Historical Perspective on Molecular Insights and Therapeutic Advances. [PDF]

Int J Mol Sci
Somai S, Aloh CH, King DE, Copeland WC.
europepmc   +1 more source

Unveiling Peripheral Immune Dysfunction in Parkinson’s Disease through Analysis of Blood-based Mitochondrial DNA Copy Number [PDF]

Longfei Wang, Ji-Ru Han, Liam G. Fearnley, Michael Milton, Haloom Rafehi, Joshua Reid, Zachary F. Gerring, Shashank Masaldan, Tali Lang, Terence P. Speed, Melanie Bahlo   +10 more
openalex   +1 more source

Maternally transmitted antigens are codominantly expressed by mouse cells containing two kinds of mitochondrial DNA. [PDF]

, 1987
John R. Rodgers, Roger Smith, R R Rich
openalex   +1 more source

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

Advanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song, Kimberly Seaman, Amel Sassi, Chun‐Yu Lin, Tiankuo Chu, Liyun Wang, Yu Sun, Lidan You   +7 more
wiley   +1 more source

An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice. [PDF]

Nat Commun
Marques E, Burr SP, Casey AM, Stopforth RJ, Yu CS, Turner K, Wolf DM, Dilucca M, Paupe V, Chowdhury SR, Tyrrell VJ, Kramer R, Kanse YM, Pednekar C, Powell CA, Stewart JB, Prudent J, Murphy MP, Minczuk M, O'Donnell VB, Bryant CE, Chinnery PF, Kaser A, von Kriegsheim A, Ryan DG.   +24 more
europepmc   +1 more source

The interplay between DNA damage response and mitochondrial dysfunction in radiotherapy

Shuhua Yang, Yuke Li, Jinlang Zhang, AiHua Shen, Burong Hu, Junfang Yan   +5 more
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source