Results 281 to 290 of about 495,836 (314)
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Mobility in the mitochondrial electron transport chain
Biochemistry, 1985The role of lateral diffusion in mitochondrial electron transport has been investigated by measuring the diffusion coefficients for lipid, cytochrome c, and cytochrome oxidase in membranes of giant mitoplasts from cuprizone-fed mice using the technique of fluorescence redistribution after photobleaching (FRAP).
J, Hochman +2 more
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Mitochondrial electron transport chain defect presenting as hypoglycemia
The Journal of Pediatrics, 1997A profoundly deaf female infant was found to have hypoglycemia and lactic acidemia after an episode of decreased oral intake and vomiting. Electron transport chain (ETC) enzyme studies revealed a combination defect of complexes I, III, and IV in liver but not in skeletal muscle.
M L, Freckmann +6 more
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Anticancer Drugs Targeting the Mitochondrial Electron Transport Chain
Antioxidants & Redox Signaling, 2011Mitochondria are emerging as highly intriguing organelles showing promise but that are yet to be fully exploited as targets for anticancer drugs.A group of compounds that induce mitochondrial destabilization, thereby affecting the physiology of cancer cells, has been defined and termed 'mitocans.' Based on their mode of action of targeting in and ...
Rohlena, Jakub +3 more
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Immobilized mitochondrial electron transport particle for NADH determination
Biotechnology and Bioengineering, 1980AbstractNonphosphorylating electron transport particles (ETP) prepared from beef heart mitochondrion were immobilized in agar gel. The immobilized ETP showed an oxidase activity to both NADH and succinate. The immobilized ETP was reusable. An electrochemical device for the determination of either NADH or succinate was assembled consisting of the ...
M, Aizawa, M, Wada, S, Kato, S, Suzuki
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Proton translocation coupled to mitochondrial electron transport
Biochemical Society Transactions, 1984particularly useful in ApH studies (Kano & Fendler, 1978; Clement & Could, 1981). The fluorescence change corresponding to given pH changes can be calibrated in individual mitochondria by equilibrating them after microinjection in media containing the protonophoric uncoupler FCCP at various pH values. As shown in Fig.
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Mitochondrial Electron Transport and Plant Stress
2010Due to the sessile nature of plants, it is crucial for their survival and growth that they can handle a constantly changing, and thus stressful, ambient environment by modifying their structure and metabolism. The central metabolism of plants is characterized by many alternative options for metabolic pathways, which allow a wide range of adjustments of
Rasmusson, Allan G, Møller, Ian Max
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THE SUPEROXIDE ANION AS ELECTRON DONOR TO THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN
Photochemistry and Photobiology, 1977Abstract— In isolated respiratory multienzyme complexes of beef heart mitochondria the b‐type cytochromes can be photoreduced in presence of flavin via the superoxide anion. O‐2 does not reduce cytochrome c1. In an anaerobic system, FMNH2 formed by irradiation with blue light in presence of EDTA reduces cytochromes b and c1 The possible implication of ...
Ninnemann, H. +2 more
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Inhibition of mitochondrial electron-transport systems by nor-isoguaiacin
Biochemical Pharmacology, 1973Abstract The effects of a new constituent isolated from the Creosote Bush, norisoguaiacin, on the activities of mitochondrial NADH-oxidase and succinoxidase systems were determined. Nor-isoguaiacin was found to be a potent inhibitor of both mitochondrial electron-transport systems, but did not inhibit cytochrome-oxidase. Preliminary data suggest that
R S, Pardini +4 more
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Sites of inhibition of mitochondrial electron transport by rhein
Biochemical Pharmacology, 1989The effect of rhein on the oxygen consumption, oxidative phosphorylation, ATPase activity and redox state of electron carriers of rat liver mitochondria has been studied. Rhein inhibits ADP- and uncoupler-stimulated respiration on various NAD-linked substrates and succinate, but stimulates state 4 respiration of mitochondria respiring on succinate ...
A, Floridi, S, Castiglione, C, Bianchi
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[57] Mitochondrial electron-transport inhibitors
1979Publisher Summary This chapter discusses the inhibitors of mitochondrial electron transport. Certain inhibitors act in the cytochrome b–c 1 region and in the flavoprotein region. This chapter provides an overview on the inhibitors of NADH oxidation.
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