Results 291 to 300 of about 495,836 (314)

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport

Biochemical Pharmacology, 1983
Adriamycin (ADM) was found to have a two-step mode of action on the cardiac mitochondrial membrane. (1) An interaction with cardiolipin (CL) resulted in the formation of an ADM-CL complex able to transfer electrons from NADH to cytochrome c (cyt.c) as well as coenzyme Q (CoQ).
Goormaghtigh, Erik, Pollakis, Georges, Ruysschaert, Jean Marie   +2 more
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Mitochondrial Electron Transport: The Random Collision Model

1987
Data are presented which represent the experimental basis for the random collision model of mitochondrial electron transport. The random collision model rejects the notion that permanent assemblies or transient aggregates of redox components are necessary to account for the sequence or rate of electron transport in the inner membrane.
Charles R. Hackenbrock, Sharmila Shaila Gupte, Brad Chazotte   +2 more
openaire   +1 more source

The role of Coenzyme Q in mitochondrial electron transport

Mitochondrion, 2007
In mitochondria, most Coenzyme Q is free in the lipid bilayer; the question as to whether tightly bound, non-exchangeable Coenzyme Q molecules exist in mitochondrial complexes is still an open question. We review the mechanism of inter-complex electron transfer mediated by ubiquinone and discuss the kinetic consequences of the supramolecular ...
LENAZ, GIORGIO, FATO, ROMANA, FORMIGGINI, GABRIELLA, GENOVA, MARIA LUISA   +3 more
openaire   +2 more sources

The H⁺/site ratio of mitochondrial electron transport

Journal of Cellular Physiology, 1976
AbstractThe number of H+ ejected during passage of 2e− through each energy‐conserving site of the mitochondrial respiratory chain (the H+/site ratio) was measured in three ways. In each case transmembrane movements of endogenous phosphate were minimized.
M D, Brand, B, Reynafarje, A L, Lehininger   +2 more
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Sites of inhibition of mitochondrial electron transport by cadmium

Chemico-Biological Interactions, 1993
Cadmium is an extremely toxic environmental contaminant having a long half-life in humans. The greatest accumulation occurs in the liver and kidneys. Since mitochondria are the most sensitive targets, the effect of cadmium on the oxygen consumption and on the redox state of electron carriers of rat liver mitochondria has been evaluated.
S, Miccadei, A, Floridi
openaire   +2 more sources

Mitochondrial Electron Transport in Peronosporales.

Journal of Phytopathology, 1978
P. C. Scheepens, H. Fehrmann
openaire   +2 more sources

Electron Transport in the Mitochondrial Respiratory Chain

2014
The metabolic capacity of the eukaryotic cell to convert free energy contained in nutrients into ATP is a process accomplished by a multistep system: the mitochondrial respiratory chain. This chain involves a series of electron-transferring enzymes and redox co-factors, whose biochemical characterization is the collective result of more than 50 years ...
openaire   +1 more source

The effect of Zn2+ ions on mitochondrial electron transport

Archives of Biochemistry and Biophysics, 1974
Abstract Zn 2+ ions linearly inhibit the electron transport in uncoupled mitochondria, Mg 2+ /ATP submitochondrial particles, and electron transport complex III between ubiquinone and the b cytochromes. A second effect is observed in coupled mitochondria only, where less than 4 μ m Zn 2+ causes a respiratory stimulation and a reduction of the b
openaire   +2 more sources

Hexestrol antagonism of mitochondrial electron transport

Biochimica et Biophysica Acta, 1962
L S, DIETIRCH, I L, YERO
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Mitochondrial reverse electron transport in myeloid cells perpetuates neuroinflammation

ABSTRACTSustained smouldering, or low grade, activation of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis (MS)1. Distinct metabolic and mitochondrial features guide the activation and the diverse functional states of myeloid cells2.
L, Peruzzotti-Jametti, C M, Willis, R, Hamel, G, Krzak, J A, Reisz, H A, Prag, V, Wu, Y, Xiang, A M R, van den Bosch, A M, Nicaise, L, Roth, G R, Bates, H, Huang, A E, Vincent, C, Frezza, C, Viscomi, J C, Marioni, A, D'Alessandro, Z, Takats, M P, Murphy, S, Pluchino   +20 more
openaire   +2 more sources