The mitochondrial genome characteristics of Coronocyclus coronatus (Looss, 1900) and comparative analysis with other strongylid nematodes. [PDF]
Hao Y, Xia Y, Ma L, Hao Z, Li B, Bu Y.
europepmc +1 more source
Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source
Characteristics and Phylogenetic Considerations of the Newly Sequenced Mitochondrial Genome of Teratoscincus scincus (Gekkota: Sphaerodactylidae). [PDF]
Ge Z, Zhang Z, Mu Z, Zhong L.
europepmc +1 more source
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin +25 more
wiley +1 more source
The complete mitochondrial genome of <i>Psyllaephagus populi</i> (Hymenoptera: Encyrtidae). [PDF]
Aishan Z +4 more
europepmc +1 more source
Disulfide‐Bridged Ru Complex–Mediated Photo‐Disulfidptosis for Colorectal Cancer Therapy
In this work, a binuclear ruthenium complex, RuSSRu was developed for efficient colorectal cancer (CRC) treatment. The synergistic interaction between disulfidptosis and lysosomal damage‐induced apoptosis induced by RuSSRu amplified tumor cell death. This innovative approach offers a potent therapeutic strategy for CRC.
Simeng He +8 more
wiley +1 more source
Complete mitochondrial genome of <i>Carabus brandti</i> (Coleoptera: Carabidae) and phylogenetic analysis. [PDF]
Pan C, Liu JF.
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Complete mitochondrial genome and phylogenetic position of the gall aphid <i>Chaetogeoica ulmidrupa</i> (Hemiptera: Aphididae). [PDF]
Wang X, Wu J, Yonezawa T, Ren Z.
europepmc +1 more source

