Results 271 to 280 of about 704,132 (300)
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UCP2 muscle gene transfer modifies mitochondrial membrane potential
International Journal of Obesity, 2001The aim of this work was to evaluate the effect of uncoupling protein 2 (UCP2) muscle gene transfer on mitochondrial activity.Five week-old male Wistar rats received an intramuscular injection of plasmid pXU1 containing UCP2 cDNA in the right tibialis anterior muscles. Left tibialis anterior muscles were injected with vehicle as control. Ten days after
A, Marti +4 more
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Mitochondrial membrane potential after low-power laser irradiation
Lasers in Medical Science, 2004We used the lipophilic cationic fluorescent dye 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl-benzimidazol-carbocyanine iodide (JC-1) to determine mitochondrial membrane potential (mdeltapsi) in Hep-2 cells after irradiation with low-power laser (lambda=635 nm).
R, Bortoletto +5 more
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Mitochondrial Membrane Potential and Dynamics
2011Mitochondria are essential for neuronal homeostasis and their dysfunction causes neurodegeneration. Mitochondrial bioenergetics and dynamics ensure ATP supply and Ca2+ buffering throughout neuronal processes, regulating and being reciprocally modulated by synaptic activity.
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Preserved motor axonal membrane potential in mitochondrial disease
Journal of Neurology, Neurosurgery & Psychiatry, 2010Mitochondrial disorders are characterised by protean neurological manifestations including peripheral neuropathy. The neuropathy is typically an axonal process, with a proposed mechanism being degradation of the membrane potential of the axon due to dysfunction of energy-dependent Na(+)/K(+) ATPase pump.
K, Ng, S, Winter, C, Sue, D, Burke
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Measurement of Mitochondrial Membrane Potential and Proton Leak
2009The major component of mitochondrial electrochemical potential gradient of protons is the mitochondrial membrane potential (DeltaPsi), and hence it is a suitable parameter for assessment of mitochondrial function. Dissipation of the mitochondrial membrane potential causes uncoupling of the electron transport through the respiratory chain and the ...
Serviddio G., Sastre J.
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A Miniaturized Homogenous Assay of Mitochondrial Membrane Potential
ASSAY and Drug Development Technologies, 2011Mitochondrial dysfunction is increasingly associated with disease states. These organelles, responsible for adenosine triphosphate production, have been targeted for improved function in such diseases as Parkinson's, Alzheimer's, type 2 diabetes, and sarcopenia.
Aurawan, Vongs +4 more
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Novel Methods for Measuring the Mitochondrial Membrane Potential
2015The mitochondrial membrane potential is a critical parameter for understanding mitochondrial function, but it is challenging to quantitate with current methodologies which are based on the accumulation of cation indicators. Recently we have introduced a new methodology based on the redox poise of the b-hemes of the bc 1 complex.
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Measurement of Nanoparticle-Induced Mitochondrial Membrane Potential Alterations
2018Mitochondria hold a critical role in cell metabolism and homeostasis. Mitochondrial injury plays central part in deciding cell fate especially in programmed cell death pathways. Various nanomaterials lead to different cell death modalities by inducing mitochondrial injury.
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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