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Measuring mitochondrial membrane potential
The EMBO JournalMitochondrial function determines the balance between health and disease, making understanding their bioenergetics an increasingly important focus across biomedical research.
Oscar Tovar-Ferrero +4 more
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Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors [PDF]
Frontiers in Pharmacology, 2021 Mitochondria are the main bioenergetic organelles of cells. Exposure to chemicals targeting mitochondria therefore generally results in the development of toxicity. The cellular response to perturbations in cellular energy production is a balance between
Huan Yang +8 more
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Analysis of mitochondrial membrane potential, ROS, and calcium
Molecules and Cells: Mitochondria play a central role in cellular energy metabolism and signaling, and their dysfunction is associated with a wide range of diseases. Therefore, assessing mitochondrial function is essential for understanding their role in various cellular ...
Hye-Kyung Park, Byoung Heon Kang
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Frontiers in Cell and Developmental Biology, 2022 Mitochondria are biosynthetic, bioenergetic, and signaling organelles with a critical role in cellular physiology. Dysfunctional mitochondria are associated with aging and underlie the cause of a wide range of diseases, from neurodegeneration to cancer ...
Karthik Vasan +7 more
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Mitochondrial membrane potential [PDF]
Analytical Biochemistry, 2018 The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III and IV) is an essential component in the process of energy storage during oxidative phosphorylation. Together with the proton gradient (ΔpH), ΔΨm forms the transmembrane potential of hydrogen ions which is harnessed to make ATP.
Ljubava D, Zorova +11 more
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Molecular Medicine, 2022 Background Thrombocytopenia is a feared complication of preeclampsia (PE) that can additionally complicate the disease course and that carries a poor prognosis.
Bjoern F. Kraemer +7 more
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Effect of the Mitochondrial Membrane Permeability Transition Pore Promoter Atractyloside on Mitochondrial Damage and Tenderness of Postmortem Beef [PDF]
Shipin Kexue, 2023 The objective of this study was to investigate the effect of atractyloside, a promoter of the mitochondrial membrane permeability transition pore (MPTP), on mitochondrial membrane permeability, cristae structure, cytochrome c release and tenderness of ...
LIU Chunmei, WEI Qichao, HAN Dong, LI Xia, ZHANG Chunhui, HUANG Feng
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Thioflavin T indicates mitochondrial membrane potential in mammalian cells
Biophysical Reports, 2023 The fluorescent benzothiazole dye thioflavin T (ThT) is widely used as a marker for protein aggregates, most commonly in the context of neurodegenerative disease research and diagnosis.
Emily Skates +4 more
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Using flow cytometry for mitochondrial assays
MethodsX, 2020 The understanding of how different cell types adapt their metabolism in the face of challenges has been attracting the attention of researchers for many years. Recently, immunologists also started to focus on how the metabolism of immune cells can impact
Lauar de Brito Monteiro +3 more
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Biology, 2022 S-15176 difumarate salt, a derivative of the anti-ischemic metabolic drug trimetazidine, has been intensively studied for its impact on cellular metabolism in animal models of ischemia-reperfusion injury of the liver, heart, spinal cord, and other organs.
Natalia V. Belosludtseva +5 more
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