Results 21 to 30 of about 474,230 (265)

Two hit mitochondrial-driven model of synapse loss in neurodegeneration

open access: yesNeurobiology of Disease, 2021
In healthy neurons, a mitochondrial membrane potential gradient exists whereby membrane potential is highest in the soma and decreases with distance from the nucleus.
Sergei V. Baranov   +3 more
doaj   +1 more source

Mitochondrial membrane studies using impedance spectroscopy with parallel pH monitoring. [PDF]

open access: yesPLoS ONE, 2014
A biological microelectromechanical system (BioMEMS) device was designed to study complementary mitochondrial parameters important in mitochondrial dysfunction studies.
Divya Padmaraj   +4 more
doaj   +1 more source

Evaluating Mitochondrial Membrane Potential in Cells

open access: yesBioscience Reports, 2007
Permeant cationic fluorescent probes are widely employed to monitor mitochondrial transmembrane potential and its changes. The application of such potential-dependent probes in conjunction with both fluorescence microscopy and fluorescence spectroscopy allows the monitoring of mitochondrial membrane potential in individual living cells as well as in ...
SOLAINI, GIANCARLO   +3 more
openaire   +3 more sources

Non-Mammalian Vertebrates: Distinct Models to Assess the Role of Ion Gradients in Energy Expenditure

open access: yesFrontiers in Endocrinology, 2017
Animals store metabolic energy as electrochemical gradients. At least 50% of mammalian energy is expended to maintain electrochemical gradients across the inner mitochondrial membrane (H+), the sarcoplasmic reticulum (Ca++), and the plasma membrane (Na ...
Caroline E. Geisler   +2 more
doaj   +1 more source

Mitochondrial Membrane Potential in Aging Cells

open access: yesNeurosignals, 2001
Decreased mitochondrial membrane potential (DeltaPsi(M)) has been found in a variety of aging cell types from several mammalian species. The physiological significance and mechanisms of the decreased DeltaPsi(M) in aging are not well understood. This review considers the generation of DeltaPsi(M) and its role in ATP generation together with factors ...
M M, Sugrue, W G, Tatton
openaire   +2 more sources

Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease

open access: yesMarine Drugs, 2017
Meretrix meretrix oligopeptides (MMO) derived from shellfish have important medicinal properties. We previously obtained MMO from alcalase by hydrolysis processes.
Fangfang Huang   +4 more
doaj   +1 more source

Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms

open access: yeseLife
Mitochondrial membrane potential directly powers many critical functions of mitochondria, including ATP production, mitochondrial protein import, and metabolite transport.
Yeyun Ouyang   +19 more
doaj   +1 more source

Mitochondrial membrane potential in cardiac myocytes

open access: yesPhysiological Research, 2002
Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield ...
L, Skárka, B, Ostádal
openaire   +2 more sources

Effect of electroacupuncture on mitochondrial function in mice with Parkinson’s disease

open access: yes针刺研究, 2021
Objective To observe the effect of electroacupuncture(EA) on behavior, tyrosine hydroxylase(TH), mitochondrial complexes Ⅰ—Ⅳ, mitochondrial membrane potential and mitochondrial ultrastructure of Parkinson's disease(PD) mice, so as to explore its ...
HUANG Kai   +4 more
doaj  

Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism

open access: yesFrontiers in Physiology, 2018
Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single ...
Alexis R. Díaz-Vegas   +12 more
doaj   +1 more source

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