Results 141 to 150 of about 280,461 (302)
Advanced Healthcare Materials, EarlyView.Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo +6 more
wiley +1 more source
Cysteine-based crosslinking approach for characterization of oligomeric pore-forming proteins in the mitochondrial membranes. [PDF]
Methods Enzymol, 2021 Zhang Z, Huang B, Zhang XC, Lin J.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
The mitochondrial membrane system
Progress in Biophysics and Molecular Biology, 1972 J M, Palmer, D O, Hall
openaire +2 more sources
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
The Role of Phospholipids in Mitochondrial Dynamics and Associated Diseases
Frontiers in Bioscience-LandmarkThe bioenergetic machinery of the cell is protected and structured within two layers of mitochondrial membranes. The mitochondrial inner membrane is extremely rich in proteins, including respiratory chain complexes, substrate transport proteins, ion ...
Solenn Plouzennec +2 more
doaj +1 more source
Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
Advanced Healthcare Materials, EarlyView.ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
Routes for Potassium Ions across Mitochondrial Membranes: A Biophysical Point of View with Special Focus on the ATP-Sensitive K+ Channel. [PDF]
Biomolecules, 2021 Kravenska Y, Checchetto V, Szabo I.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Influence of Microbial Metabolites on the Nonspecific Permeability of Mitochondrial Membranes under Conditions of Acidosis and Loading with Calcium and Iron Ions. [PDF]
Biomedicines, 2021 Fedotcheva N, Olenin A, Beloborodova N.
europepmc +1 more source