Results 161 to 170 of about 280,461 (302)

Membrane proteins in the outer mebrane of plastids and mitochondria [PDF]

open access: yes, 2006
Channels of the plastid and mitochondrial outer membranes facilitate the turnover of molecules and ions via these membranes. Although channels have been studied many questions pertaining to the whole diversity of plastid and mitochondrial channels in ...
Ilkavets, Iryna
core  

Mitochondrial membrane chromatography: Discovery of mitochondrial targeting modulators

open access: yesJournal of Pharmaceutical Analysis
Mitochondria are fundamental organelles that play a crucial role in cellular energy metabolism, substance metabolism, and various essential cellular signaling pathways. The dysfunction of mitochondria is significantly implicated in the onset and progression of aging, neurodegenerative diseases, metabolic disorders, and tumors, thereby rendering ...
Wu Su   +10 more
openaire   +2 more sources

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates

open access: yesThe EMBO Journal
During PINK1- and Parkin-mediated mitophagy, autophagy adaptors are recruited to damaged mitochondria to promote their selective degradation. Autophagy adaptors such as optineurin (OPTN) and NDP52 facilitate mitophagy by recruiting the autophagy ...
Zi Yang   +6 more
doaj   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta   +3 more
wiley   +1 more source

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

open access: yesAdvanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed   +9 more
wiley   +1 more source

Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes. [PDF]

open access: yesSci Rep, 2020
Farrugia MY   +8 more
europepmc   +1 more source

Characterization of mitochondrial C₁-tetrahydrofolate synthase transcript and protein expression in adult and embryonic mammalian tissues and the role of the mitochondrial one-carbon pathway in the cytoplasmic methyl cycle

open access: yes, 2008
textIn eukaryotes, folate-dependent one-carbon (1-C) metabolism is composed of two parallel pathways compartmentalized to either the cytoplasm or mitochondria.
Pike, Schuyler Todd, 1966-
core  

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

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