Results 81 to 90 of about 419,034 (232)

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

MITOCHONDRIAL DNA POLYMORPHISMS AND FERTILITY IN BEEF CATTLE [PDF]

, 2002
Two regions of mitochondrial DNA, D-loop and ND-5 were characterized using polymerase chain reaction – restriction fragment length polymorphism (PCR-RFLP) involving 422 beef cattle of Hereford and composite breeds from Wokalup’s ...
A.J, Lymbery, J.M, Cummins, ., Sutarno, RCA, Thompson   +3 more
core  

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

A Case of Infantile Reversible Cytochrome C Oxidase Deficiency Myopathy in Taiwan: A 4-Year Follow-Up

Case Reports in Medicine
Infantile reversible cytochrome c oxidase (COX) deficiency myopathy is a mitochondrial rare disease with onset age of first day to three months with symptoms of generalized muscle weakness and severe hypotonia. Despite its initial serious conditions, the
Yu-Ting Ma, Ju-Li Lin, Ming-Wei Lai, I-Jun Chou, Mao-Sheng Hwang   +4 more
doaj   +1 more source

Inflammatory myopathies in the elderly [PDF]

Einstein (São Paulo), 2008
Infl ammatory myopathies were analysed according to its differentpresentations, which include dermatomyositis, polymyositis andinclusion body myopathies, especially related to old age.
Edgard Torres dos Reis Neto, Daniel Feldman Pollak   +1 more
doaj  

Muscle fatigue in patients with severe long COVID: A 2‐year follow‐up study

PM&R, EarlyView.
Abstract Background Fatigue is recognized as one of the most persistent and debilitating symptoms of long COVID, affecting both functionality and quality of life. However, its long‐term effects, especially beyond the first year after infection, remain poorly understood.
Isabella da Silva Almeida, Leandro Gomes de Jesus Ferreira, Marco Aurélio Vaz, Rochelle Rocha Costa, Nicolas Babault, Rita de Cássia Marqueti, João Luiz Quagliotti Durigan   +6 more
wiley   +1 more source

Clinical and pathological characteristics of mitochondrial myopathy and the screening value of simplified serum lactic acid exercise test

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To analyze clinical and pathological characteristics of mitochondrial myopathy (MM) in 15 patients, and to study the value of simplified serum lactic acid exercise test in the screening of mitochondrial myopathy.
Xiao-fen ZHU, Ji DING, Xiao-qi ZHU, Yuan-yuan LI, Ai-lian DU   +4 more
doaj  

Long-read sequencing for diagnosis of genetic myopathies

BMJ Neurology Open
Genetic myopathies are caused by pathogenic variants in >300 genes across the nuclear and mitochondrial genomes. Although short-read next-generation sequencing (NGS) has revolutionised the diagnosis of genetic disorders, large and/or complex genetic ...
Gianina Ravenscroft, Roula Ghaoui, Ryan Davis, Kishore Raj Kumar, Karl Ng, Marina Kennerson, Dennis Yeow, Ira Deveson, Laura Ivete Rudaks, Pak Leng Cheong   +9 more
doaj   +1 more source

ColVI myopathies: where do we stand, where do we go?

Skeletal Muscle, 2011
Collagen VI myopathies, caused by mutations in the genes encoding collagen type VI (ColVI), represent a clinical continuum with Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM) at each end of the spectrum, and less well-defined ...
Allamand Valérie, Briñas Laura, Richard Pascale, Stojkovic Tanya, Quijano-Roy Susana, Bonne Gisèle   +5 more
doaj   +1 more source