Results 1 to 10 of about 1,131,582 (303)
Impairments in mitochondrial dynamics and morphology in skeletal muscle of breast cancer patients after a single paclitaxel administration [PDF]
Standard chemotherapy regimens for patients with breast cancer are based on epirubicin–cyclophosphamide (EC) and paclitaxel (TAX) administrations. While it has been shown that first EC administration impairs mitochondrial homeostasis, the isolated ...
Joris Mallard +10 more
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The Role of Mitochondria in Mediation of Skeletal Muscle Repair
Musculoskeletal health is directly linked to independence and longevity, but disease and aging impairs muscle mass and health. Complete repair after a pathological or physiological muscle injury is critical for maintaining muscle function, yet muscle ...
Stephen E. Alway +2 more
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Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig +6 more
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Cardiorenal Syndrome: Ebony and Ivory
The kidney and cardiovascular systems are closely interconnected and interact continuously in both physiological and pathological conditions [...]
Nans Florens
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Mitochondrial Properties in Skeletal Muscle Fiber
Mitochondria are the primary source of energy production and are implicated in a wide range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on mitochondria for energy supplements.
Han Dong, Shih-Yin Tsai
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Exercise produces oxidants from a variety of intracellular sources, including NADPH oxidases (NOX) and mitochondria. Exercise-derived reactive oxygen species (ROS) are beneficial, and the amount and location of these ROS is important to avoid muscle ...
Alejandra Espinosa +2 more
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The Role of Mitophagy in Skeletal Muscle Damage and Regeneration
Mitochondria are cellular organelles that play an essential role in generating the chemical energy needed for the biochemical reactions in cells. Mitochondrial biogenesis, i.e., de novo mitochondria formation, results in enhanced cellular respiration ...
Eirini Chatzinikita +4 more
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Glycolysis Mediated Sarcoplasmic Reticulum Ca Signal Regulates Mitochondria Ca during Skeletal Muscle Contraction [PDF]
PURPOSE This study was to investigate the Glycolysis mediated sarcoplasmic reticulum (SR) Ca2+ signal regulates mitochondria Ca2+ during skeletal muscle contraction by using glycolysis inhibitor.
Dae-Ryoung Park
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Mitochondria play a principal role in metabolism, and mitochondrial respiration is an important process for producing adenosine triphosphate. Recently, we showed the possibility that the muscle‐specific protein myoglobin (Mb) interacts with mitochondrial
Rikuhide Koma +6 more
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Mitochondrial dysfunction: roles in skeletal muscle atrophy
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle health, and damage to mitochondria can lead to a series of pathophysiological changes.
Xin Chen +11 more
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