Vitamin D, Mitochondria, and Muscle [PDF]
Vitamin D was initially identified as the cure for rickets. Its metabolism and its action on bone and growth plate are now well recognized. 1,25-Dihydroxyvitamin D3 (1,25(OH)2D) probably has, however, a much wider spectrum of activities because the vitamin D receptor (VDR) is expressed in virtually all nucleated cells, the activating CYP27B1 or 1 ...
Roger, Bouillon, Annemieke, Verstuyf
openaire +2 more sources
Exercise produces oxidants from a variety of intracellular sources, including NADPH oxidases (NOX) and mitochondria. Exercise-derived reactive oxygen species (ROS) are beneficial, and the amount and location of these ROS is important to avoid muscle ...
Alejandra Espinosa +2 more
doaj +1 more source
The Role of Mitophagy in Skeletal Muscle Damage and Regeneration
Mitochondria are cellular organelles that play an essential role in generating the chemical energy needed for the biochemical reactions in cells. Mitochondrial biogenesis, i.e., de novo mitochondria formation, results in enhanced cellular respiration ...
Eirini Chatzinikita +4 more
doaj +1 more source
Glycolysis Mediated Sarcoplasmic Reticulum Ca Signal Regulates Mitochondria Ca during Skeletal Muscle Contraction [PDF]
PURPOSE This study was to investigate the Glycolysis mediated sarcoplasmic reticulum (SR) Ca2+ signal regulates mitochondria Ca2+ during skeletal muscle contraction by using glycolysis inhibitor.
Dae-Ryoung Park
doaj +1 more source
Human cachexia induces changes in mitochondria, autophagy and apoptosis in the skeletal muscle [PDF]
Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life.
Alcantara, P. S. +9 more
core +1 more source
Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding +8 more
core +1 more source
Endurance training facilitates myoglobin desaturation during muscle contraction in rat skeletal muscle. [PDF]
At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O2 to the mitochondria. Accordingly, intracellular O2 tension (PmbO2) markedly declines in order to increase muscle O2 uptake (mVO2).
Furuichi, Yasuro +9 more
core +1 more source
Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity [PDF]
Animals, especially ectotherms, are highly sensitive to the temperature of their surrounding environment. Extremely high temperature, for example, induces a decline of average performance of conspecifics within a population, but individual heterogeneity ...
Anderson, Graeme J. +4 more
core +1 more source
Creatine kinase in energy metabolic signaling in muscle [PDF]
There has been much debate on the mechanism of regulation of mitochondrial ATP synthesis to balance ATP consumption during changing cardiac workloads. A key role of creatine kinase (CK) isoenzymes in this regulation of oxidative phosphorylation and in ...
Johannes H. G. M. van Beek, Olav Kongas
core +2 more sources
Mitochondria play a principal role in metabolism, and mitochondrial respiration is an important process for producing adenosine triphosphate. Recently, we showed the possibility that the muscle‐specific protein myoglobin (Mb) interacts with mitochondrial
Rikuhide Koma +6 more
doaj +1 more source

