Results 41 to 50 of about 264,171 (312)

Young Age and Concomitant Cannabis (THC) and Ethanol (EtOH) Exposure Enhances Rat Brain Damage Through Decreased Cerebral Mitochondrial Respiration

Molecules
The reason why young people taking concomitantly cannabis (THC) and ethanol (EtOH) are more prone to stroke is underresearched. To investigate whether an underlying mechanism of increased brain damage could be an impaired mitochondrial function, this ...
Véronique Quenardelle, Anne-Laure Charles, Anne Charloux, Jean-Sébastien Raul, Valérie Wolff, Bernard Geny   +5 more
doaj   +1 more source

Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress [PDF]

, 2017
In recent years evolutionary ecologists have become increasingly interested in the effects of reactive oxygen species (ROS) on the life-histories of animals.
A Kuznetsov, A Logan, A Logan, AS Veskoukis, B D’Autreaux, B Kalyanaraman, B Pathi, BM Kennedy, C Alonso-Alvarez, C Alonso-Alvarez, C Selman, CM Porteous, D Costantini, D Harman, DH Nussey, DK Dowling, G Barja, GA Rivera-Ingraham, GP Bienert, HM Cochemé, HM Cochemé, JCL Brown, JR Speakman, KJ McGraw, Kuznetsov, LB Martin, M De Block, M Hachiya, M Lopez-Torres, MF Ross, P Horak, P Monaghan, P Niethammer, P Pacher, RA Smith, RS Balaban, S Kaushik, SY Kim, T von Schantz   +38 more
core   +3 more sources

Acute Effects of Polyphenol-Rich Fruit Juice on Exercise Capacity and Vessels Dilatation in Healthy Humans: A Randomized, Controlled, Crossover Study

Applied Sciences
This study examined the acute effects of polyphenol (PP)-rich fruit juice supplementation on the exercise capacity of healthy humans. Thirty-five healthy, sedentary volunteers participated in this randomized, controlled, crossover study. They performed a
Olivier Rouyer, Anne-Laure Charles, Cyril Auger, Samy Talha, Emmanuel Andres, Anne Charloux, Valerie Schini-Kerth, Bernard Geny   +7 more
doaj   +1 more source

Rapid isolation of respiring skeletal muscle mitochondria using nitrogen cavitation

Frontiers in Physiology, 2023
Methods of isolating mitochondria commonly utilise mechanical force and shear stress to homogenize tissue followed by purification by multiple rounds of ultracentrifugation.
Awais Z. Younis, Gareth G. Lavery, Mark Christian, Craig L. Doig   +3 more
doaj   +1 more source

Accuracy of Rhythm Diagnostic Systems’ MultiSense^® in Detection of Arterial Oxygen Saturation and Respiratory Rate During Hypoxia in Humans: Effects of Skin Color and Device Localization

Sensors
The continuous monitoring of oxygen saturation (SpO2) and respiratory rates (RRs) are major clinical issues in many cardio-respiratory diseases and have been of tremendous importance during the COVID-19 pandemic.
Charles Evrard, Amina El Attaoui, Cristina Pistea, Irina Enache, Mark Marriott, Louis Mayaud, Anne Charloux, Bernard Geny   +7 more
doaj   +1 more source

Progression of myopathology in Kearns-Sayre syndrome [PDF]

, 1992
We report on the progression of myopathology by comparing two biopsies from a patient with a Kearns-Sayre-Syndrome. The first biopsy was taken in 1979 and showed 10% ragged-red fibers.
B. Meurers, CT Moraes, H Reichmann, Heinz Reichmann, I Nonaka, JA Morgan-Hughes, M. Naumann, P. Seibel, R. Gold, T. Klopstock, U. Walter, V Dubowitz   +11 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. [PDF]

, 2015
Lysosomes are classically viewed as vesicular structures to which cargos are delivered for degradation. Here, we identify a network of dynamic, tubular lysosomes that extends throughout Drosophila muscle, in vivo. Live imaging reveals that autophagosomes
Davis, Graeme W, Hauswirth, Anna G, Johnson, Alyssa E, Shu, Huidy, Tong, Amy   +4 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Liability of Health Professionals Using Sensors, Telemedicine and Artificial Intelligence for Remote Healthcare

Sensors
In the last few decades, there has been an ongoing transformation of our healthcare system with larger use of sensors for remote care and artificial intelligence (AI) tools.
Marie Geny, Emmanuel Andres, Samy Talha, Bernard Geny   +3 more
doaj   +1 more source