Results 31 to 40 of about 264,171 (312)
Maintaining Muscle Mitochondria via Transsynaptic Signaling [PDF]
Developmental Cell, 2012 Dominant VAPB mutations are implicated in neurodegenerative disease, including amyotrophic lateral sclerosis and spinal muscular atrophy. In the current issue, Han et al. (2012) uncover a mechanism through which the secreted VAPB MSP domain regulates actin organization and mitochondrial function in muscle cells through LAR and Robo receptor activation.
Long, Jennifer B., Van Vactor, David
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BiologyThe anti-inflammatory and analgesic properties of cannabis might be useful to treat muscle diseases, including those linked or not to alcohol. Nevertheless, delta 9 tetrahydrocannabinol (THC) and ethanol (EtOH), often used concomitantly, can have ...
Anne-Laure Charles +8 more
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Ageing of skeletal muscle extracellular matrix and mitochondria: finding a potential link
Annals of Medicine, 2023 Aim: To discuss the progress of extracellular matrix (ECM) characteristics, mitochondrial homeostasis, and their potential crosstalk in the pathogenesis of sarcopenia, a geriatric syndrome characterized by a generalized and progressive reduction in ...
Lubing Cai +4 more
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Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission [PDF]
, 2015 Defects of mitochondrial dynamics are emerging causes of neurological disease. In two children presenting with severe neurological deterioration following viral infection we identified a novel homozygous STAT2 mutation, c.1836C4A (p.Cys612Ter), using ...
Anderson, G +14 more
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Comparing Electron Leak in Vertebrate Muscle Mitochondria [PDF]
Integrative and Comparative Biology, 2018 Mitochondrial electron transfer for oxidative ATP regeneration is linked to reactive oxygen species (ROS) production in aerobic eukaryotic cells. Because they can contribute to signaling as well as oxidative damage in cells, these ROS have profound impact for the physiology and survival of the organism.
Treberg, J.R. +5 more
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MoleculesGlyphosate (GP) and its derivatives are present in almost all environments and suspected to induce acute and chronic kidney injuries. This public health issue is relatively underexplored.
Rayhana Rihani +3 more
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PLoS ONE, 2017 Skeletal muscle resistance to insulin is related to accumulation of lipid-derived products, but it is not clear whether this accumulation is caused by skeletal muscle mitochondrial dysfunction. Diabetes and obesity are reported to have a selective effect
Nicola Lai +2 more
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The effect of melatonin on lipid peroxide oxidation, oxidative modification of proteins and mitochondria swelling in the skeletal muscle tissue of rats under alloxan diabetes [PDF]
The Ukrainian Biochemical Journal, 2018 The aim of the investigation was to study the effect of melatonin on of peroxide lipid oxidation, the oxidative modification of proteins and the mitochondria swelling in skeletal muscle tissue of rats under alloxan diabetes.
I. V. Gerush +2 more
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Oxidative phosphorylation efficiency, proton conductance and reactive oxygen species production of liver mitochondria correlates with body mass in frogs [PDF]
, 2015 ody size is a central biological parameter affecting most biological processes (especially energetics) and mitochondria is a key organelle controlling metabolism and is also the cell's main source of chemical energy.
Dumet, A. +5 more
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Response of Skeletal Muscle Mitochondria to Hypoxia [PDF]
Experimental Physiology, 2003 This review explores the current concepts relating the structural and functional modifications of skeletal muscle mitochondria to the molecular mechanisms activated when organisms are exposed to a hypoxic environment. In contrast to earlier assumptions it is now established that permanent or long‐term exposure to severe environmental hypoxia decreases ...
Hoppeler, Hans +3 more
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