Results 151 to 160 of about 914,673 (333)

S5.3d How mitochondrial complex I proteins in Candida albicans moderate phagocytosis and the production of pro-inflammatory cytokines in murine macrophages and dendritic cells [PDF]

, 2022
Xiaodong She, Pengyi Zhang, Richard Calderone, Weida Liu, Dongmei Li   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins. [PDF]

Cells, 2023
Mark M, Klein O, Zhang Y, Das K, Elbaz A, Hazan RN, Lichtenstein M, Lehming N, Schuldiner M, Pines O.   +9 more
europepmc   +1 more source

A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability [PDF]

, 2016
Hana Antonická, Karine Choquet, Zhen‐Yuan Lin, Anne‐Claude Gingras, Claudia L. Kleinman, Eric A. Shoubridge   +5 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Notoginsenoside R1 Attenuates H/R Injury in H9c2 Cells by Maintaining Mitochondrial Homeostasis

Current Issues in Molecular Biology
Mitochondrial homeostasis is crucial for maintaining cellular energy production and preventing oxidative stress, which is essential for overall cellular function and longevity.
Yuanbo Xu, Piao Wang, Ting Hu, Ke Ning, Yimin Bao   +4 more
doaj   +1 more source

Endogenous TOM20 Proximity Labeling: A Swiss-Knife for the Study of Mitochondrial Proteins in Human Cells. [PDF]

Int J Mol Sci, 2023
Meurant S, Mauclet L, Dieu M, Arnould T, Eyckerman S, Renard P.   +5 more
europepmc   +1 more source

Supplementary Material for: The Role of Intestinal Fatty Acid Binding Proteins in Protecting Cells from Fatty Acid Induced Impairment of Mitochondrial Dynamics and Apoptosis

, 2018
Suparna Sarkar‐Banerjee, Sourav Chowdhury, Dwipanjan Sanyal, Tanya Mitra, Susanta Sinha Roy, Krishnananda Chattopadhyay   +5 more
openalex   +1 more source

The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH‐ubiquinone oxidoreductase) [PDF]

, 2004
Prasanth Potluri, Nagendra Yadava, Immo E. Scheffler   +2 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source