Results 51 to 60 of about 587,110 (190)

BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria. [PDF]

open access: yesPLoS ONE, 2012
Mieap, a p53-inducible protein, controls mitochondrial quality by repairing unhealthy mitochondria. During repair, Mieap induces the accumulation of intramitochondrial lysosomal proteins (designated MALM for Mieap-induced accumulation of lysosome-like ...
Yasuyuki Nakamura   +7 more
doaj   +1 more source

Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3

open access: yesFrontiers in Physiology, 2018
A growing number of studies have demonstrated the role of post-translational modifications of proteins, particularly acetylation, in human diseases including neurodegenerative and cardiovascular diseases, diabetes, cancer, and in aging.
Rebecca M. Parodi-Rullán   +2 more
doaj   +1 more source

Mitochondrial Oxidative Damage in Chicken Skeletal Muscle Induced by Acute Heat Stress

open access: yesThe Journal of Poultry Science, 2007
Mitochondria have long been known to play a critical role in maintaining bioenergetic status under physiological conditions. Our previous studies have shown that acute heat stress increases production of mitochondrial reactive oxygen species (ROS) in ...
Ahmad Mujahid   +6 more
doaj   +1 more source

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

open access: yesCell Reports, 2017
Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling, and their dysfunction has been linked to numerous diseases.
Marcel Morgenstern   +17 more
doaj   +1 more source

Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62

open access: yesNature Communications
Aneuploidy, or aberrant chromosomal content, disrupts cellular proteostasis through altered expression of numerous proteins. Aneuploid cells accumulate SQSTM1/p62-positive cytosolic bodies, exhibit impaired protein folding, and show altered proteasomal ...
Prince Saforo Amponsah   +10 more
doaj   +1 more source

Distinct or Overlapping Areas of Mitochondrial Thioredoxin 2 May Be Used for Its Covalent and Strong Non-Covalent Interactions with Protein Ligands [PDF]

open access: gold, 2023
Charalampos Ntallis   +4 more
openalex   +1 more source

Mitochondrial Translocation of Protein Kinase C δ in Phorbol Ester-induced Cytochrome c Release and Apoptosis [PDF]

open access: hybrid, 2000
Pradip K. Majumder   +7 more
openalex   +1 more source

p53 and Tumor Necrosis Factor α Regulate the Expression of a Mitochondrial Chloride Channel Protein [PDF]

open access: hybrid, 1999
Ester Fernández‐Salas   +4 more
openalex   +1 more source

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