Results 211 to 220 of about 119,249 (261)
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Monoamine Oxidase and Mitochondrial Respiration
Journal of Neurochemistry, 1999Abstract : Mitochondrial defects encompassing complexes I‐IV of the electron transport chain characterize a relatively large number of neurodegenerative diseases. The relationships between mitochondrial lesions and recently described genetic alterations have not yet been defined.
G, Cohen, N, Kesler
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ROLE OF PHOSPHOLIPIDS IN MITOCHONDRIAL RESPIRATION
Canadian Journal of Biochemistry and Physiology, 1959The addition of heated snake venom solutions to suspensions of rat liver, kidney, or brain mitochondria results in an initial stimulation of the rate of respiration, which is approximately the same for a variety of substrates, followed by a rapid decline.The presence of phospholipase A in heated snake venom is demonstrated by the formation of ...
E, PETRUSHKA +2 more
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The effect of acetaldehyde on mitochondrial respiration
Experimental Cell Research, 1963Abstract The inhibiting effect of acetaldehyde on the pyruvate oxidation in mitochondria from various tissues has been investigated. The following sequence was found as to the degree of aldehyde inhibition: liver Liver and kidney mitochondria oxidize acetaldehyde rapidly compared with muscle and brain mitochondria.
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Regulation of mitochondrial respiration in senescence
Journal of Cellular Physiology, 1972AbstractThe ADP‐stimulated (State 3) respiration of myocardial mitochondria with glutamate‐malate, glutamate‐pyruvate, palmitylcarnitine and β‐hydroxybutyrate as substrates declined in rats after the age of 20 months. There was no significant decline in pyruvate‐malate, α‐oxoglutarate, palmityl‐CoA, succinate and ascorbate cytochrome c oxidation ...
J C, Chen, J B, Warshaw, D R, Sanadi
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Control of mitochondrial respiration in muscle
Molecular and Cellular Biochemistry, 1988Control of mitochondrial respiration depends on ADP availability to the F1-ATPase. An electrochemical gradient of ADP and ATP across the mitochondrial inner membrane is maintained by the adenine nucleotide translocase which provides ADP to the matrix for ATP synthesis and ATP for energy-dependent processes in the cytosol.
J B, McMillin, D F, Pauly
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Uncoupling Mitochondrial Respiration for Diabesity
Rejuvenation Research, 2016Until recently, the mechanism of adaptive thermogenesis was ascribed to the expression of uncoupling protein 1 (UCP1) in brown and beige adipocytes. UCP1 is known to catalyze a proton leak of the inner mitochondrial membrane, resulting in uncoupled oxidative metabolism with no production of adenosine triphosphate and increased energy expenditure.
James W, Larrick +2 more
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Effect of Ryanodine on Mitochondrial Respiration
Pharmacology, 2008Ryanodine is a pharmacological agent that stimulates calcium leakage into the cytoplasm resulting in an increase in tension. In skeletal muscle, ryanodine acts primarily on the sarcoplasmic reticulum whereas in smooth muscle, the sites of action are less clear.
R M, Levin +4 more
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Lactate as a fuel for mitochondrial respiration
Acta Physiologica Scandinavica, 2000Lactate production in skeletal muscle has now been studied for nearly two centuries and still its production and functional role at rest and during muscle contraction is a subject of debate. Historically, skeletal muscle was seen mainly as the site of lactate production during contraction and lactate production associated with a lack of muscle ...
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Parathyroid Hormone and Mitochondrial Respiration
Endocrinology, 1964Parathyroid hormone added in vitro stimulates anion-dependent respiration in isolated liver and kidney mitochondria. This response depends upon Mg++ (or Mn++) and substrate and is inhibited by uncouplers and inhibitors of electron transport but not by oligomycin or triethyltin, inhibitors of oxidative phosphorylation.
M, FANG, H, RASMUSSEN
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Mitochondrial Respiration and Oxygen Tension
2017Measurements of respiration and oxygen tension in plant organs allow a precise understanding of mitochondrial capacity and function within the context of cellular oxygen metabolism. Here we describe methods that can be routinely used for the isolation of intact mitochondria, and the determination of respiratory electron transport, together with ...
Daniel S, Shaw +3 more
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