Results 11 to 20 of about 337,106 (263)

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion

open access: yesmBio, 2020
Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Kylie Jacobs   +2 more
doaj   +1 more source

Design and Synthesis of a Mitochondria-Targeting Radioprotectant for Promoting Skin Wound Healing Combined with Ionizing Radiation Injury

open access: yesPharmaceuticals, 2022
Wound healing is seriously retarded when combined with ionizing radiation injury, because radiation-induced excessive reactive oxygen species (ROS) profoundly affect cell growth and wound healing. Mitochondria play vital roles not only as cellular energy
Zaizhi Du   +9 more
doaj   +1 more source

Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy

open access: yesNeural Plasticity, 2020
Sensorineural hearing loss (SNHL) becomes an inevitable worldwide public health issue, and deafness treatment is urgently imperative; yet their current curative therapy is limited. Auditory neuropathies (AN) were proved to play a substantial role in SNHL
Baoyi Feng   +9 more
doaj   +1 more source

A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

open access: yeseLife, 2020
Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx).
Samantha Ebersoll   +4 more
doaj   +1 more source

Aging-Related Changes in the Ultrastructure of Hepatocytes and Cardiomyocytes of Elderly Mice Are Enhanced in ApoE-Deficient Animals

open access: yesCells, 2021
Biological aging is associated with various morphological and functional changes, yet the mechanisms of these phenomena remain unclear in many tissues and organs. Hyperlipidemia is among the factors putatively involved in the aging of the liver and heart.
Małgorzata Łysek-Gładysińska   +9 more
doaj   +1 more source

Disturbance of Mitochondrial Dynamics and Mitochondrial Therapies in Atherosclerosis

open access: yesLife, 2021
Mitochondrial dysfunction is associated with a wide range of chronic human disorders, including atherosclerosis and diabetes mellitus. Mitochondria are dynamic organelles that undergo constant turnover in living cells.
Alexander M. Markin   +7 more
doaj   +1 more source

High-Throughput Genomic Data Reveal Complex Phylogenetic Relationships in Stylosanthes Sw (Leguminosae)

open access: yesFrontiers in Genetics, 2021
Allopolyploidy is widely present across plant lineages. Though estimating the correct phylogenetic relationships and origin of allopolyploids may sometimes become a hard task. In the genus Stylosanthes Sw.
Maria Alice Silva Oliveira   +14 more
doaj   +1 more source

A patatin-like phospholipase is important for mitochondrial function in malaria parasites

open access: yesmBio, 2023
Plasmodium parasites rely on a functional electron transport chain (ETC) within their mitochondrion for proliferation, and compounds targeting mitochondrial functions are validated antimalarials.
Emma Pietsch   +12 more
doaj   +1 more source

Towards a Synthetic Mitochondrion

open access: yesCHIMIA, 2018
Our group at the University of Bern uses biochemical and biophysical techniques to unravel details of the molecular mechanism of membrane proteins.
Olivier Biner   +3 more
doaj   +1 more source

Acute Succinate Administration Increases Oxidative Phosphorylation and Skeletal Muscle Explosive Strength via SUCNR1

open access: yesFrontiers in Veterinary Science, 2022
Endurance training and explosive strength training, with different contraction protein and energy metabolism adaptation in skeletal muscle, are both beneficial for physical function and quality of life.
Guli Xu   +7 more
doaj   +1 more source

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