Results 11 to 20 of about 226,740 (385)

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion [PDF]

open access: yesmBio, 2020
Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Kylie Jacobs   +2 more
doaj   +4 more sources

Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery

open access: yesNature Communications, 2021
The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang   +6 more
doaj   +2 more sources

Of mitochondrion and COVID-19

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction.
Khalid Omer Alfarouk   +15 more
doaj   +2 more sources

AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria [PDF]

open access: yesCell Death and Disease
Lipid droplet (LD) -mitochondrion contacts play a crucial role in regulating energy metabolism and fatty acid oxidation in skeletal muscle cells. However, the proteins that regulate these interactions remain poorly understood.
Lupeng Chen   +5 more
doaj   +2 more sources

ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division

open access: yesNature Communications, 2021
Mitochondrial division is not an autonomous event but involves multiple organelles, including the endoplasmic reticulum (ER) and lysosomes. Whereas the ER drives the constriction of mitochondrial membranes, the role of lysosomes in mitochondrial division
Peter K Kim
exaly   +2 more sources

Towards a Synthetic Mitochondrion

open access: yesCHIMIA, 2018
Our group at the University of Bern uses biochemical and biophysical techniques to unravel details of the molecular mechanism of membrane proteins.
Olivier Biner   +3 more
doaj   +5 more sources

What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion?

open access: yesFrontiers in Cell and Developmental Biology, 2019
A large body of literature supports the idea that nuclear factor kappa B (NF-κB) signaling contributes to not only immunity, but also inflammation, cancer, and nervous system function. However, studies on NF-κB activity in mitochondrial function are much
Benedict C Albensi
exaly   +2 more sources

Mitochondrion

open access: yesDefinitions, 2020
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Mitochondria contain distinctive ribosomes, transfer RNAs, amino acyl t-RNA synthetases, and elongation and termination factors ...
Juli Peretó
semanticscholar   +2 more sources

Protein translocation pathways of the mitochondrion [PDF]

open access: bronzeFEBS Letters, 2000
The biogenesis of mitochondria depends on the coordinated import of precursor proteins from the cytosol coupled with the export of mitochondrially coded proteins from the matrix to the inner membrane. The mitochondria contain an elaborate network of protein translocases in the outer and inner membrane along with a battery of chaperones and processing ...
Carla M. Koehler
openalex   +5 more sources

The return of the mitochondrion [PDF]

open access: goldThe Biochemist, 2005
For a fresh-faced (well, apart from the beard) PhD graduate in 1989, mitochondrial bioenergetics might have seemed a strange choice of research path. Flushed with the general acceptance of the chemiosmotic theory, many felt that the area had passed its heyday. With the publication of its ‘bible’ (Bioenergetics, the definitive textbook by David Nicholls)
Chris E. Cooper
openalex   +2 more sources

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