Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion [PDF]
mBio, 2020 Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Arrizabalaga, Gustavo +2 more
core +3 more sources
Optical Properties and Interference Effects of the Lens Mitochondrion
Membranes, 2023 The lens mitochondrion of the tree shrew, located along the optical pathway between the lens and photoreceptors, has been investigated. The results suggest that the lens mitochondrion acts as a quasi-bandgap or imperfect photonic crystal.
Felix Margadant +3 more
doaj +1 more source
Cells, 2021 Emerging evidence suggests that mitochondrion–endoplasmic reticulum (ER) and mitochondrion–lipid droplet (LD) contact sites are critical in regulating lipid metabolism in cells.
Xiaowen Ma +4 more
doaj +1 more source
Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
Nature Communications, 2021 The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang +6 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction.
Khalid Omer Alfarouk +15 more
doaj +1 more source
Inventory and Evolution of Mitochondrion-localized Family A DNA Polymerases in Euglenozoa
Pathogens, 2020 The order Trypanosomatida has been well studied due to its pathogenicity and the unique biology of the mitochondrion. In Trypanosoma brucei, four DNA polymerases, namely PolIA, PolIB, PolIC, and PolID, related to bacterial DNA polymerase I (PolI), were ...
Ryo Harada +10 more
doaj +1 more source
Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology
Frontiers in Cell and Developmental Biology, 2022 Mitochondria, in symbiosis with the host cell, carry out a wide variety of functions from generating energy, regulating the metabolic processes, cell death to inflammation.
Arpita Chowdhury +3 more
doaj +1 more source
In silico simulation of reversible and irreversible swelling of mitochondria: The role of membrane rigidity [PDF]
, 2020 Mitochondria have been widely accepted as the main source of ATP in the cell. The inner mitochondrial membrane (IMM) is important for the maintenance of ATP production and other functions of mitochondria.
Arieli +48 more
core +1 more source
A Note on the Consequences of a Hot Mitochondrion: Some Recent Developments and Open Questions
Біофізичний вісник, 2020 Background: Chrétien and co-workers (PLOS Biology. 2018;16(1):e2003992) recently suggested that the mitochondrion might possibly be hotter than its surrounding (by as much as 10°C).
Peyman Fahimi +5 more
doaj +1 more source
A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes
eLife, 2020 Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx).
Samantha Ebersoll +4 more
doaj +1 more source