Results 11 to 20 of about 92,731 (139)

Inventory and Evolution of Mitochondrion-localized Family A DNA Polymerases in Euglenozoa [PDF]

open access: yes, 2020
The order Trypanosomatida has been well studied due to its pathogenicity and the unique biology of the mitochondrion. In Trypanosoma brucei, four DNA polymerases, namely PolIA, PolIB, PolIC, and PolID, related to bacterial DNA polymerase I (PolI), were ...
Akinori YABUKI   +12 more
core   +2 more sources

Gazing at Translocation in the Mitochondrion [PDF]

open access: yesCell, 2008
Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondrion via molecular machines called translocons on the outer and inner mitochondrial membranes. Alder et al. (2008b) examine protein translocation into intact mitochondria by adapting fluorescent techniques first used to study translocation in the endoplasmic ...
Susan Walsh, Carla M. Koehler
openaire   +3 more sources

Lead and the mitochondrion [PDF]

open access: yesPostgraduate Medical Journal, 1975
Summary In studies on the distribution of lead in rats given drinking water containing lead acetate at concentrations: 0, 100, 500, 1000 and 5000 μgPb/l for one year, no change was observed in the organ distribution of lead, or in the subcellular distribution of lead in the organelles in the heart. The mitochondrial enzyme,
openaire   +3 more sources

Cell Biology of the Mitochondrion [PDF]

open access: yesGenetics, 2017
AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M   +2 more
openaire   +4 more sources

Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels [PDF]

open access: yes, 2001
Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these ...
Benne R.   +29 more
core   +1 more source

Analysis of two genomes from the mitochondrion-like organelle of the intestinal parasite Blastocystis: complete sequences, gene content, and genome organization. [PDF]

open access: yes, 2008
Acquisition of mitochondria by the ancestor of all living eukaryotes represented a crucial milestone in the evolution of the eukaryotic cell. Nevertheless, a number of anaerobic unicellular eukaryotes have secondarily discarded certain mitochondrial ...
Clark, C Graham, Pérez-Brocal, Vicente
core   +2 more sources

Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]

open access: yes, 2018
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin   +3 more
core   +1 more source

The bloodstream differentiation - division of Trypanosoma brucei studied using mitochondrial markers [PDF]

open access: yes, 1997
In the bloodstream of its mammalian host, the African trypanosome Trypanosoma brucei undergoes a life cycle stage differentiation from a long, slender form to a short, stumpy form.
Bangs J. D.   +10 more
core   +2 more sources

3-D Ultrastructure of O. tauri: Electron Cryotomography of an Entire Eukaryotic Cell [PDF]

open access: yes, 2007
The hallmark of eukaryotic cells is their segregation of key biological functions into discrete, membrane-bound organelles. Creating accurate models of their ultrastructural complexity has been difficult in part because of the limited resolution of light
A Al-Amoudi   +68 more
core   +10 more sources

Towards a Synthetic Mitochondrion

open access: yesCHIMIA, 2018
Our group at the University of Bern uses biochemical and biophysical techniques to unravel details of the molecular mechanism of membrane proteins. Of special interest are the large multi-subunit complexes of the universally conserved respiratory chain and the ATP synthase that are found in mitochondria and aerobic bacteria.
Biner, Olivier Felix   +3 more
openaire   +5 more sources

Home - About - Disclaimer - Privacy