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Organellar Evolution: A Path from Benefit to Dependence
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
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Plant mitoviruses belong to Mitoviridae family and consist of positive single-stranded RNA genomes replicating exclusively in host mitochondria.
Dario Di Silvestre +6 more
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A Note on the Consequences of a Hot Mitochondrion: Some Recent Developments and Open Questions
Background: Chrétien and co-workers (PLOS Biology. 2018;16(1):e2003992) recently suggested that the mitochondrion might possibly be hotter than its surrounding (by as much as 10°C).
Peyman Fahimi +5 more
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Quality control of the mitochondrion [PDF]
Mitochondria are essential organelles that execute and coordinate various metabolic processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes to disease. Proper organellar function depends on the biogenesis and maintenance of mitochondria and its >1,000 proteins.
Ng, Matthew +2 more
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Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy
Sensorineural hearing loss (SNHL) becomes an inevitable worldwide public health issue, and deafness treatment is urgently imperative; yet their current curative therapy is limited. Auditory neuropathies (AN) were proved to play a substantial role in SNHL
Baoyi Feng +9 more
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Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Kylie Jacobs +2 more
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AbstractDiverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of a mitochondrion. The image magnifies a portion of the mitochondrion by one million times, showing the location and form of membranes and individual macromolecules ...
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A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes
Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx).
Samantha Ebersoll +4 more
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Maturases can specifically bind to intron-containing pre-RNAs, folding them into catalytic structures that facilitate intron splicing in vivo. Plants possess four nuclear-encoded maturase-related factors (nMAT1-nMAT4) and some maturases have been shown ...
Kaijian Fan +9 more
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Lead and the mitochondrion [PDF]
Summary In studies on the distribution of lead in rats given drinking water containing lead acetate at concentrations: 0, 100, 500, 1000 and 5000 μgPb/l for one year, no change was observed in the organ distribution of lead, or in the subcellular distribution of lead in the organelles in the heart. The mitochondrial enzyme,
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