Results 11 to 20 of about 344,643 (260)

Of mitochondrion and COVID-19 [PDF]

open access: goldJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
La COVID-19, une maladie pandémique causée par une infection virale, est associée à un taux de mortalité élevé. La plupart des signes et symptômes, par exemple tempête de cytokines, déséquilibres électrolytiques, thromboembolie, etc., sont liés à un dysfonctionnement mitochondrial.
Ali M AlQahtani   +2 more
exaly   +6 more sources

The mitochondrion as a hammer [PDF]

open access: goldEvolution: Education and Outreach, 2020
AbstractThis is a review of Mitonuclear Ecology by Geoffrey E. Hill, which discusses the potential role of mitochondrial-nuclear (mitonuclear) interactions in key evolutionary processes.
Logan W. Cole
openalex   +3 more sources

The selfish mitochondrion [PDF]

open access: yesCell Calcium, 2021
Mitochondria match ATP supply to fluctuations in cellular energy requirements. Cellular energy requirements are often signaled to mitochondria by increases in the cytoplasmic concentration of Ca2+ ions. These increases in Ca2+ reach the mitochondrial matrix to regulate the proteins, enzymes and transporters required for mitochondrial ATP synthesis ...
McCarron, John G., Wilson, Calum
openaire   +3 more sources

Is Myelin a Mitochondrion? [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 2012
It has been hypothesized that myelin acts like a mitochondrion, generating ATP across the membranes of its sheath. By calculating the proton motive force across the myelin membrane based on known values for the pH and membrane potential of the oligodendrocyte, we find that insufficient energy could be harvested from proton flow across the myelin ...
Harris, Julia J, Attwell, David
openaire   +2 more sources

Quality control of the mitochondrion [PDF]

open access: yesDevelopmental Cell, 2021
Mitochondria are essential organelles that execute and coordinate various metabolic processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes to disease. Proper organellar function depends on the biogenesis and maintenance of mitochondria and its >1,000 proteins.
Ng, Matthew   +2 more
openaire   +3 more sources

Mitochondrion [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2010
AbstractDiverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of a mitochondrion. The image magnifies a portion of the mitochondrion by one million times, showing the location and form of membranes and individual macromolecules ...
openaire   +2 more sources

Lead and the mitochondrion [PDF]

open access: yesPostgraduate Medical Journal, 1975
Summary In studies on the distribution of lead in rats given drinking water containing lead acetate at concentrations: 0, 100, 500, 1000 and 5000 μgPb/l for one year, no change was observed in the organ distribution of lead, or in the subcellular distribution of lead in the organelles in the heart. The mitochondrial enzyme,
openaire   +2 more sources

Gazing at Translocation in the Mitochondrion [PDF]

open access: yesCell, 2008
Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondrion via molecular machines called translocons on the outer and inner mitochondrial membranes. Alder et al. (2008b) examine protein translocation into intact mitochondria by adapting fluorescent techniques first used to study translocation in the endoplasmic ...
Walsh, Susan, Koehler, Carla M.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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