Results 11 to 20 of about 367,263 (290)

Of mitochondrion and COVID-19 [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction.
Khalid O Alfarouk   +2 more
exaly   +9 more sources

Towards a Synthetic Mitochondrion [PDF]

open access: yesCHIMIA, 2018
Our group at the University of Bern uses biochemical and biophysical techniques to unravel details of the molecular mechanism of membrane proteins.
Olivier Biner   +3 more
doaj   +6 more sources

Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing

open access: yesCell Reports, 2017
Summary: A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for identification of variants present at the single-mitochondrion level in individual mouse and human
Jai-Yoon Sul   +2 more
exaly   +4 more sources

Pyrophosphate homeostasis in multiple subcellular compartments is essential in Plasmodium falciparum [PDF]

open access: yesmBio
Pyrophosphate is a byproduct of numerous cellular reactions that use ATP or other nucleoside triphosphates to synthesize DNA, RNA, protein, and various molecules.
Ikechukwu Nwankwo, Hangjun Ke
doaj   +2 more sources

The selfish mitochondrion [PDF]

open access: yesCell Calcium, 2021
Mitochondria match ATP supply to fluctuations in cellular energy requirements. Cellular energy requirements are often signaled to mitochondria by increases in the cytoplasmic concentration of Ca2+ ions. These increases in Ca2+ reach the mitochondrial matrix to regulate the proteins, enzymes and transporters required for mitochondrial ATP synthesis ...
McCarron, John G., Wilson, Calum
openaire   +4 more sources

Optical Properties and Interference Effects of the Lens Mitochondrion

open access: yesMembranes, 2023
The lens mitochondrion of the tree shrew, located along the optical pathway between the lens and photoreceptors, has been investigated. The results suggest that the lens mitochondrion acts as a quasi-bandgap or imperfect photonic crystal.
Felix Margadant   +3 more
doaj   +1 more source

Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery

open access: yesNature Communications, 2021
The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang   +6 more
doaj   +1 more source

Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism

open access: yesCells, 2021
Emerging evidence suggests that mitochondrion–endoplasmic reticulum (ER) and mitochondrion–lipid droplet (LD) contact sites are critical in regulating lipid metabolism in cells.
Xiaowen Ma   +4 more
doaj   +1 more source

Inventory and Evolution of Mitochondrion-localized Family A DNA Polymerases in Euglenozoa

open access: yesPathogens, 2020
The order Trypanosomatida has been well studied due to its pathogenicity and the unique biology of the mitochondrion. In Trypanosoma brucei, four DNA polymerases, namely PolIA, PolIB, PolIC, and PolID, related to bacterial DNA polymerase I (PolI), were ...
Ryo Harada   +10 more
doaj   +1 more source

Is Myelin a Mitochondrion? [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 2012
It has been hypothesized that myelin acts like a mitochondrion, generating ATP across the membranes of its sheath. By calculating the proton motive force across the myelin membrane based on known values for the pH and membrane potential of the oligodendrocyte, we find that insufficient energy could be harvested from proton flow across the myelin ...
Harris, Julia J, Attwell, David
openaire   +2 more sources

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