Results 191 to 200 of about 337,106 (263)

Transcriptome analysis of Edwardsiella piscicida during intracellular infection reveals excludons are involved with the activation of a mitochondrion-like energy generation program

Andre Lanza, Satoshi Kimura, Ikuo Hırono, Kazutoshi Yoshitake, Shigeharu Kinoshita, Shuichi Asakawa   +5 more
openalex   +1 more source

Significant correlation between refractive index and activity of mitochondria: single mitochondrion study

, 2015
Keisuke Haseda, Keita Kanematsu, Keiichi Noguchi, H Saito, Norihiro Umeda, Yoshihiro Ohta   +5 more
openalex   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Plastid, mitochondrion and nuclear genome coverage in 12 Ostreococcus tauri strains and estimation of mitochondrial and plastid genome copy number per haploid nuclear genome. from Single Cell Ecogenomics reveals mating types of individual cells and ssDNA viral infections in the Smallest Photosynthetic Eukaryotes

, 2019
Luiz Felipe Rocha Benites, Nicole Poulton, Karine Labadie, Michael E. Sieracki, Nigel Grimsley, Gwenaël Piganeau   +5 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Zero-shot segmentation using embeddings from a protein language model identifies functional regions in the human proteome. [PDF]

PLoS Comput Biol
Sangster AG, Dufault C, Qu H, Le D, Forman-Kay JD, Moses AM.   +5 more
europepmc   +1 more source

Disruption of Mitochondrial Networks by the Human Cytomegalovirus UL37 Gene Product Viral Mitochondrion-Localized Inhibitor of Apoptosis

, 2002
A. Louise McCormick, Vanessa Smith, Dar C. Chow, Edward S. Mocarski   +3 more
openalex   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Draft genome sequence of <i>Prototheca bovis</i> strain P18 isolated from cattle in Japan. [PDF]

Microbiol Resour Announc
Akiba M, Sekizuka T, Yasutomi I, Fujii Y, Uchida I.   +4 more
europepmc   +1 more source