Measurement of δ<sup>1</sup>-Pyrroline-5-Carboxylic Acid in Plant Extracts for Physiological and Biochemical Studies. [PDF]
Forlani G, Trupia F.
europepmc +1 more source
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source
Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles. [PDF]
Coceano G +6 more
europepmc +1 more source
miR‐185‐5p derived from UC‐MSC exosomes via hypoxic suspension culture promotes scarless wound healing in mice by precisely regulating collagen I/III regeneration. Exosomes derived from UC‐MSCs under a three‐dimensional bioreactor and hypoxic conditions were injected into the skin wounds of mice.
Lihua Yang +14 more
wiley +1 more source
Eukaryogenesis From FECA to LECA: Radical Steps Along the Way. [PDF]
Speijer D.
europepmc +1 more source
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
3D Mitochondria Shape Library for Optical Microscopy (3DMSL): A multimodal dataset for deep learning based mitochondrial analysis. [PDF]
Punnakkal AR +5 more
europepmc +1 more source
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
From Ancient Philosophy to Endosymbiotic Theory: The Bacterial Origin and Key Role of Mitochondria in Immune Responses. [PDF]
Mpakosi A +13 more
europepmc +1 more source
Zero-shot segmentation using embeddings from a protein language model identifies functional regions in the human proteome. [PDF]
Sangster AG +5 more
europepmc +1 more source

