Results 21 to 30 of about 337,106 (263)

Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing

Cell Reports, 2017
Summary: A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for identification of variants present at the single-mitochondrion level in individual mouse and human
Jacqueline Morris, Young-Ji Na, Hua Zhu, Jae-Hee Lee, Hoa Giang, Alexandra V. Ulyanova, Gordon H. Baltuch, Steven Brem, H. Isaac Chen, David K. Kung, Timothy H. Lucas, Donald M. O’Rourke, John A. Wolf, M. Sean Grady, Jai-Yoon Sul, Junhyong Kim, James Eberwine   +16 more
doaj   +1 more source

Dietary Supplementation With High Fiber Alleviates Oxidative Stress and Inflammatory Responses Caused by Severe Sepsis in Mice Without Altering Microbiome Diversity

Frontiers in Physiology, 2019
In this study, we demonstrated the effects of a high-fiber diet on intestinal lesions, oxidative stress and systemic inflammation in a murine model of endotoxemia.
Yuanyuan Zhang, Aili Dong, Keliang Xie, Yonghao Yu   +3 more
doaj   +1 more source

Visualization of a Mammalian Mitochondrion by Coherent X-ray Diffractive Imaging

Scientific Reports, 2017
We report a three dimensional (3D) quantitative visualization of a mammalian mitochondrion by coherent x-ray diffractive imaging (CXDI) using synchrotron radiation.
Yoonhee Kim, Chan Kim, Ou Young Kwon, Daewoong Nam, Sang Soo Kim, Jae Hyun Park, Sunam Kim, Marcus Gallagher-Jones, Yoshiki Kohmura, Tetsuya Ishikawa, Changyong Song, Giyoong Tae, Do Young Noh   +12 more
doaj   +1 more source

Autophagy Dysfunction and Oxidative Stress, Two Related Mechanisms Implicated in Retinitis Pigmentosa

Frontiers in Physiology, 2018
Retinitis pigmentosa (RP) is one of the most common clinical subtypes of retinal degeneration (RD), and it is a neurodegenerative disease that could cause complete blindness in humans because it ultimately affects the photoreceptors viability.
Mari-Luz Moreno, Salvador Mérida, Francisco Bosch-Morell, Francisco Bosch-Morell, María Miranda, Vincent M. Villar   +5 more
doaj   +1 more source

The complete mitochondrial genome of Pareuchiloglanis feae (Siluriformes, Sisoridae, Pareuchiloglanis): genome characterization and phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2022
Pareuchiloglanis feae is mainly distributed in Irrawaddy (China and Myanmar), Salween (China and Myanmar), and the Yangtze River drainage areas. In this study, the complete mitochondrial genome of P.
Sheng Zeng, Xue Wang, Wei Liu, Yan Xiang, Lu Zhou   +4 more
doaj   +1 more source

Intracellular position of mitochondria and chloroplasts in bundle sheath and mesophyll cells of C3 grasses in relation to photorespiratory CO2 loss

Plant Production Science, 2016
In C3 plants, photosynthetic efficiency is reduced by photorespiration. A part of CO2 fixed during photosynthesis in chloroplasts is lost from mitochondria during photorespiration by decarboxylation of glycine by glycine decarboxylase (GDC).
Yuto Hatakeyama, Osamu Ueno
doaj   +1 more source

Characterization of the leafhopper mitogenome of Mileewa alara (Hemiptera: Cicadellidae: Mileewinae) and its phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2021
The mitogenome data of leafhopper species Mileewa alara was assembled and annotated in this study. The results shows that length of M. alara is 16020 bp, consist of 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes, and one control region.
Hongli He, Maofa Yang
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of Eccentric Exercise on Skeletal Muscle Injury: From An Ultrastructure Aspect: A Review

Physical Activity and Health, 2021
The contraction of skeletal muscle (SM) plays an important role in providing power for the body to participate in physical activities. Nevertheless, unaccustomed motions, especially eccentric exercises (EE), might cause changes in ultrastructure and ...
Jianhua Ying, Xuanzhen Cen, Peimin Yu
doaj   +1 more source