Results 21 to 30 of about 382,530 (347)

Design and Synthesis of a Mitochondria-Targeting Radioprotectant for Promoting Skin Wound Healing Combined with Ionizing Radiation Injury

open access: yesPharmaceuticals, 2022
Wound healing is seriously retarded when combined with ionizing radiation injury, because radiation-induced excessive reactive oxygen species (ROS) profoundly affect cell growth and wound healing. Mitochondria play vital roles not only as cellular energy
Zaizhi Du   +9 more
doaj   +1 more source

Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy

open access: yesNeural Plasticity, 2020
Sensorineural hearing loss (SNHL) becomes an inevitable worldwide public health issue, and deafness treatment is urgently imperative; yet their current curative therapy is limited. Auditory neuropathies (AN) were proved to play a substantial role in SNHL
Baoyi Feng   +9 more
doaj   +1 more source

A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

open access: yeseLife, 2020
Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx).
Samantha Ebersoll   +4 more
doaj   +1 more source

Aging-Related Changes in the Ultrastructure of Hepatocytes and Cardiomyocytes of Elderly Mice Are Enhanced in ApoE-Deficient Animals

open access: yesCells, 2021
Biological aging is associated with various morphological and functional changes, yet the mechanisms of these phenomena remain unclear in many tissues and organs. Hyperlipidemia is among the factors putatively involved in the aging of the liver and heart.
Małgorzata Łysek-Gładysińska   +9 more
doaj   +1 more source

Mitochondrion [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2010
AbstractDiverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of a mitochondrion. The image magnifies a portion of the mitochondrion by one million times, showing the location and form of membranes and individual macromolecules ...
openaire   +2 more sources

Disturbance of Mitochondrial Dynamics and Mitochondrial Therapies in Atherosclerosis

open access: yesLife, 2021
Mitochondrial dysfunction is associated with a wide range of chronic human disorders, including atherosclerosis and diabetes mellitus. Mitochondria are dynamic organelles that undergo constant turnover in living cells.
Alexander M. Markin   +7 more
doaj   +1 more source

Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels [PDF]

open access: yes, 2001
Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these ...
Benne R.   +29 more
core   +1 more source

Lead and the mitochondrion [PDF]

open access: yesPostgraduate Medical Journal, 1975
Summary In studies on the distribution of lead in rats given drinking water containing lead acetate at concentrations: 0, 100, 500, 1000 and 5000 μgPb/l for one year, no change was observed in the organ distribution of lead, or in the subcellular distribution of lead in the organelles in the heart. The mitochondrial enzyme,
openaire   +2 more sources

Mitochondrial behaviour throughout the lytic cycle of Toxoplasma gondii [PDF]

open access: yes, 2017
Mitochondria distribution in cells controls cellular physiology in health and disease. Here we describe the mitochondrial morphology and positioning found in the different stages of the lytic cycle of the eukaryotic single-cell parasite Toxoplasma gondii.
Lemgruber, Leandro   +4 more
core   +2 more sources

High-Throughput Genomic Data Reveal Complex Phylogenetic Relationships in Stylosanthes Sw (Leguminosae)

open access: yesFrontiers in Genetics, 2021
Allopolyploidy is widely present across plant lineages. Though estimating the correct phylogenetic relationships and origin of allopolyploids may sometimes become a hard task. In the genus Stylosanthes Sw.
Maria Alice Silva Oliveira   +14 more
doaj   +1 more source

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