Results 51 to 60 of about 15,616 (228)
The FEBS Journal, Volume 293, Issue 7, Page 2086-2097, April 2026.Cells rely on mitochondria and peroxisomes to trigger antiviral defenses via the protein MAVS. This manuscript demonstrates that the robust production of antiviral effectors resulting from MAVS activation at peroxisomes is faster than at mitochondria due to a swifter oligomerization of this protein at peroxisomal membranes. These results underscore the
Bruno Ramos +4 more
wiley +1 more source
Manejo del paciente con enfermedades mitocondriales [PDF]
, 2019 Las enfermedades mitocondriales son un grupo de mutaciones englobadas dentro de las denominadas “enfermedades raras”. Son producidas por alteraciones en el mtDNA, que generan un déficit en la síntesis de ATP; la energía básica para el correcto ...
García Díez, Jorge
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The FEBS Journal, Volume 293, Issue 8, Page 2454-2477, April 2026.Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott +9 more
wiley +1 more source
Mitochondrial ultrastructural and atpase changes during the life cycle of Ascaris Suum
Memorias do Instituto Oswaldo Cruz, 1982 Ultrastructural morphology and ATPase specific activities of mitochondria isolated from 1-celled fertilized egg, 10-day embryo, 21-day infective larvae and adult body wall muscle of Ascaris suum and rat liver were determined and compared.
G. E. Rodrick +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, Volume 600, Issue 6, Page 894-909, March 2026.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, Volume 16, Issue 3, Page 450-460, March 2026.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Revista Científica, 2012 Se analizó la ultraestructura de embriones bovinos producidos in vitro durante su desarrollo temprano y tardío, mediante la técnica de microscopia electrónica de transmisión (MET). Los complejos cúmulus-ovocitos fueron aspirados de vacas sacrificadas en
Yadira Urribarrí Rodríguez +6 more
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Literature review : relationship between metabolic rate and life expectancy in mammals and birds [PDF]
, 2016 [Resumen] Os primeiros estudos nos cales os investigadores a través de hipóteses, leis e modelos se percataron de que a taxa metabólica variaba en función do tamaño foron clave para entender o papel do metabolismo no tempo de vida dunha especie.
Lombardero Marcos, Saleta
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FEBS Open Bio, Volume 16, Issue 3, Page 584-594, March 2026.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Técnicas de substituição de DNA mitocondrial para reduzir a transmissão da síndrome de leigh
Clinical and Biomedical Research, 2021 A Síndrome de Leigh (SL) é uma doença neuro-metabólica congênita, que faz parte do grupo das encefalopatias fatais, com progressão e morte dentro de 2 anos, em média.
Angelica Godoy de Fraga +1 more
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