Receptors coupled to heterotrimeric GTP-binding proteins (G proteins) are integral membrane proteins involved in the transmission of signals from the extracellular environment to the cytoplasm. The best known family of G protein-coupled receptors (GPCRs),
J. Gutkind
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IL-2 stimulation of T lymphocytes induces sequential activation of mitogen-activated protein kinases and phosphorylation of p56lck at serine-59 [PDF]
Julian D. Watts+4 more
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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor [PDF]
Sarah Traverse+4 more
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Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. [PDF]
Jianguo Wu+8 more
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Mitogen‐activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2 [PDF]
Marcus E. Peter+3 more
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Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells. [PDF]
Ellen K. Shibuya, Joan Ruderman
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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
P. Roberts, C. Der
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MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity. [PDF]
Anne M. Gardner+3 more
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