Results 151 to 160 of about 218,105 (212)

Dexamethasone regulates gene expression in chondrocytes through MKP-1 and downregulates cholesterol hydroxylases CH25H and CYP7B1. [PDF]

open access: yesInflamm Res
Lehtola T   +7 more
europepmc   +1 more source

Dissecting stress-activated protein kinase (SAPK)-signaling pathways using multiplex gene knockout HeLa cells. [PDF]

open access: yesJ Biol Chem
Ito C   +9 more
europepmc   +1 more source

Multi-Level Profiling of MAPK-Associated Genes and MicroRNAs Uncovers Regulatory Networks in Breast Cancer Subtypes. [PDF]

open access: yesInt J Mol Sci
Król-Jatręga K   +12 more
europepmc   +1 more source

Mitogen-activated protein kinases

Critical Care Medicine, 2002
The cellular control switches are regulated through an extensive network of interactive intracellular signal transduction pathways, such as the mitogen-activated protein kinase (MAPK) family. The MAPK pathways may play an important role in the inappropriate inflammatory responses that lead to systemic inflammatory response syndrome or multiple organ ...
Saman, Arbabi, Ronald V, Maier
openaire   +3 more sources

Novel mitogen-activated protein kinase kinase inhibitors

Expert Opinion on Investigational Drugs, 2011
the development of new drugs over the last few decades has targeted specific proteins thought to be a key to the disease state. MAPK kinases 1 and 2 (commonly known as MEK1-2) represent such proteins as they lie downstream of important drug targets for oncology, such as EGFR, RAS and RAF.
Mark S, Chapman, Jeffrey N, Miner
openaire   +2 more sources

Mitogen-activated protein kinase pathways

Current Opinion in Cell Biology, 1997
Nearly all cell surface receptors utilize one or more of the mitogen-activated protein kinase cascades in their repertoire of signal transduction mechanisms. Recent advances in the study of such cascades include the cloning of genes encoding novel members of the cascades, further definition of the roles of the cascades in responses to extracellular ...
M J, Robinson, M H, Cobb
openaire   +2 more sources

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