Results 201 to 210 of about 400,893 (317)

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival.

Biochemical Journal, 1998
Xiantao Wang, J. Martindale, Yusen Liu, N. Holbrook   +3 more
semanticscholar   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Curation of the Fasciola hepatica kinome as a resource for drug target discovery. [PDF]

BMC Genomics
Ajmera S, Puckelwaldt O, Stroehlein AJ, Haeberlein S.   +3 more
europepmc   +1 more source

Mitogen-Activated Protein Kinase Kinase Inhibitor [PDF]

, 2020
openaire   +1 more source

S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

Molecular and Cellular Biology, 2004
M. Pende, S. Um, Virginie Mieulet, Melanie Sticker, V. Goss, J. Mestan, Matthias Mueller, S. Fumagalli, S. Kozma, G. Thomas   +9 more
semanticscholar   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

SCAMP3-Driven Regulation of ERK1/2 and Autophagy Phosphoproteomics Signatures in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Morales-Cabán BM, Cantres-Rosario YM, Tosado-Rodríguez EL, Roche-Lima A, Meléndez LM, Boukli NM, Suarez-Arroyo IJ.   +6 more
europepmc   +1 more source

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Rice blast pathogen effector AvrPib compromises disease resistance by targeting Raf-like protein kinase OsMAPKKK72 to inhibit MAPK signaling. [PDF]

J Integr Plant Biol
Wang Z, Zhong G, Zhang B, Xie Y, Gan Y, Tang D, Wang W.   +6 more
europepmc   +1 more source